BC-NH2 [2-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine]

BC-NH2

2-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine

CLIP-tag is a modified version of SNAP-tag. It is also a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase. Instead of benzylguanine derivatives, CLIP tag is engineered to react with benzylcytosine derivatives. It can be used as a protein tag for tagging your protein of interest (POI). BC-NH2 is a carboxy-reactive building block for preparing of CLIP substrates from the NHS esters or other amine-reactive forms of labels or biological targets. This BC-NH2 building block facilities the development of various CLIP-tag substrates for labeling CLIP-tag fusion proteins for a wide range of biological applications. AAT Bioquest offers a broad range of amine-reactive fluorescent probes and other Tag probes that can be readily coupled to BC-NH2.

Protocol

COA

Catalog	Size	Price	Quantity
12562	1 mg	Price
12563	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of BC-NH2 [2-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	434.273 µL	2.171 mL	4.343 mL	21.714 mL	43.427 mL
5 mM	86.855 µL	434.273 µL	868.546 µL	4.343 mL	8.685 mL
10 mM	43.427 µL	217.136 µL	434.273 µL	2.171 mL	4.343 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	230.27 g/mol	=	mL	x	mM	=	mmol

Physical properties

Molecular weight	230.27
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	1004524-64-4

Documents

Protocol
Safety Data Sheet (Catalog 12562)
Safety Data Sheet (Catalog 12563)
Certificate of Analysis

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on November 23, 2025