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Beta-Ala-AMC

Beta-Ala-AMC is a fluorogenic substrate that might be used for detection pancreatic elastase, arylamidase and beta-alanine aminopeptidase activities. It may also be used for detecting Pseudomonas aeruginosa that have beta-alanine aminopeptidase activity. Beta-alanine aminopeptidase activity was detected in Serratia liquefaciens, Pseudomonas aeruginosa, Pseudomonas fluorescens, Burkholderia cepacia, Pseudomonas mendocina and Ochrobactrum anthropi. Therefore, beta-Ala-AMC may be used for detecting these species in food and other samples.

Spectrum

Product family

NameExcitation (nm)Emission (nm)Extinction coefficient (cm -1 M -1)
D-Ala-AMC *CAS 201847-52-1*341441-
Beta-Ala-R11050052280000

References

View all 17 references: Citation Explorer
Direct detection of cysteine peptidases for MALDI-TOF MS analysis using fluorogenic substrates.
Authors: Elpidina, Elena N and Semashko, Tatiana A and Smirnova, Yulia A and Dvoryakova, Elena A and Dunaevsky, Yakov E and Belozersky, Mikhail A and Serebryakova, Marina V and Klyachko, Elena V and Abd El-Latif, Ashraf O and Oppert, Brenda and Filippova, Irina Y
Journal: Analytical biochemistry (2019): 45-50
Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics.
Authors: Zhai, Xiang and Meek, Thomas D
Journal: Biochemistry (2018): 3176-3190
Structural and functional highlights of methionine aminopeptidase 2 from Leishmania donovani.
Authors: Bhat, Saleem Yousuf and Dey, Arijit and Qureshi, Insaf A
Journal: International journal of biological macromolecules (2018): 940-954
Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense.
Authors: Pillay, Davita and Boulangé, Alain F V and Coustou, Virginie and Baltz, Théo and Coetzer, Theresa H T
Journal: Experimental parasitology (2013): 675-84
A quantitative technique for determining proteases and their substrate specificities and pH optima in crude enzyme extracts.
Authors: Budic, Maruska and Kidric, Marjetka and Meglic, Vladimir and Cigić, Blaz
Journal: Analytical biochemistry (2009): 56-62
Page updated on October 14, 2024

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Catalog Number13202
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Physical properties

Molecular weight

282.72

Solvent

DMSO

Spectral properties

Excitation (nm)

341

Emission (nm)

441

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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