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Beta-trifluoromethylumbelliferone [7-Hydroxy-4-trifluoromethylcoumarin] *CAS 575-03-1*
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This coumarin compound is used as a calibration standard for 7-hydroxy-4-trifluoromethylcoumarin-based enzyme substrates. It has pH-dependent fluorescence.
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Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of Beta-trifluoromethylumbelliferone [7-Hydroxy-4-trifluoromethylcoumarin] *CAS 575-03-1* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 434.518 µL | 2.173 mL | 4.345 mL | 21.726 mL | 43.452 mL |
| 5 mM | 86.904 µL | 434.518 µL | 869.036 µL | 4.345 mL | 8.69 mL |
| 10 mM | 43.452 µL | 217.259 µL | 434.518 µL | 2.173 mL | 4.345 mL |
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Citations
View all 1 citations: Citation Explorer
Reduced biotransformation of polycyclic aromatic hydrocarbons (PAHs) in pollution-adapted Gulf killifish (Fundulus grandis)
Authors: Franco, Marco E and Johanning, Karla and Matson, Cole W and Lavado, Ramon
Journal: Science of The Total Environment (2021): 150854
Authors: Franco, Marco E and Johanning, Karla and Matson, Cole W and Lavado, Ramon
Journal: Science of The Total Environment (2021): 150854
References
View all 15 references: Citation Explorer
Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes
Authors: Chang TK, Crespi CL, Waxman DJ.
Journal: Methods Mol Biol (2006): 97
Authors: Chang TK, Crespi CL, Waxman DJ.
Journal: Methods Mol Biol (2006): 97
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases
Authors: Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
Journal: Drug Metab Dispos (2004): 587
Authors: Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
Journal: Drug Metab Dispos (2004): 587
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil)
Authors: Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.
Journal: Drug Metab Dispos (2004): 267
Authors: Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.
Journal: Drug Metab Dispos (2004): 267
Generation and validation of rapid computational filters for cyp2d6 and cyp3a4
Authors: Ekins S, Berbaum J, Harrison RK.
Journal: Drug Metab Dispos (2003): 1077
Authors: Ekins S, Berbaum J, Harrison RK.
Journal: Drug Metab Dispos (2003): 1077
Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10
Authors: Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J.
Journal: Drug Metab Dispos (2003): 528
Authors: Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J.
Journal: Drug Metab Dispos (2003): 528