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BG-NH2
O6-(4-Aminomethyl-benzyl)guanine
BG-NH2 is a carboxy-reactive building block for preparing of SNAP substrates from the NHS esters or other amine-reactive forms of labels or biological targets. This BG-NH2 building block facilities the development of various SNAP-tag substrates for labeling SNAP-tag fusion proteins for a wide range of biological applications. AAT Bioquest offers a broad range of amine-reactive fluorescent probes and other Tag probes that can be readily coupled to BG-NH2. The SNAP protein labeling system enables the specific, covalent attachment of virtually any molecule to a protein of interest. The SNAP-tag is a protein based on human O6-alkylguanine-DNA-alkyltransferase (hAGT). SNAP-tag substrates are fluorophores, biotin or beads conjugated to guanine or chloropyrimidine leaving groups via a benzyl linker. In the labeling reaction, the substituted benzyl group of the substrate is covalently attached to the SNAP-tag.
Chemical structure for BG-NH2 [O6-(4-Aminomethyl-benzyl)guanine].
Chemical structure for BG-NH2 [O6-(4-Aminomethyl-benzyl)guanine].
protocol
Protocol
COA
CatalogSize
Price
Quantity
125601 mg
Price
125615 mg
Price
 
Physical properties
Molecular weight270.30
SolventDMSO
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
CAS674799-96-3
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Page updated on October 13, 2025