BG Succinimidyl Ester
Ordering information
Price | |
Catalog Number | |
Unit Size | |
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Additional ordering information
Telephone | 1-800-990-8053 |
Fax | 1-800-609-2943 |
sales@aatbio.com | |
Quotation | Request |
International | See distributors |
Shipping | Standard overnight for United States, inquire for international |
Physical properties
Molecular weight | 481.47 |
Solvent | DMSO |
Storage, safety and handling
H-phrase | H303, H313, H333 |
Hazard symbol | XN |
Intended use | Research Use Only (RUO) |
R-phrase | R20, R21, R22 |
Storage | Freeze (< -15 °C); Minimize light exposure |
UNSPSC | 12171501 |
Alternative formats
BG-Maleimide |
Overview | ![]() ![]() |
See also: Amine Reactive Dyes and Probes for Conjugation, Bioconjugation, Chemical Reagents, Dyes by Functional Group
Molecular weight 481.47 |
SNAP protein labeling system enables the specific, covalent attachment of virtually any molecule to a protein of interest. The SNAP-tag is a protein based on human O6-alkylguanine-DNA-alkyltransferase (hAGT). SNAP-tag substrates are fluorophores, biotin or beads conjugated to guanine or chloropyrimidine leaving groups via a benzyl linker. In the labeling reaction, the substituted benzyl group of the substrate is covalently attached to the SNAP-tag. BG Succinimidyl Ester is an amine-reactive building block for preparing of SNAP substrates from amine-containing labels or biological targets. BG Succinimidyl Ester building block facilities the development of various SNAP-tag substrates for labeling SNAP-tag fusion proteins for a wide range of biological applications.
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of BG Succinimidyl Ester to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
1 mM | 207.697 µL | 1.038 mL | 2.077 mL | 10.385 mL | 20.77 mL |
5 mM | 41.539 µL | 207.697 µL | 415.395 µL | 2.077 mL | 4.154 mL |
10 mM | 20.77 µL | 103.849 µL | 207.697 µL | 1.038 mL | 2.077 mL |
Molarity calculator
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References
View all 50 references: Citation Explorer
Photo-SNAP-tag, a Light-Regulated Chemical Labeling System.
Authors: Cleveland, Joseph D and Tucker, Chandra L
Journal: ACS chemical biology (2020)
Authors: Cleveland, Joseph D and Tucker, Chandra L
Journal: ACS chemical biology (2020)
The covalent SNAP tag for protein display quantification and low-pH protein engineering.
Authors: Jin, Wei and Madan, Bharat and Mussman, Brooklyn K and Hailemariam, Amen T and Fahad, Ahmed S and Wolfe, Jacy R and Kwon, Young Do and Zhang, Baoshan and Shapiro, Lawrence and Kwong, Peter D and DeKosky, Brandon J
Journal: Journal of biotechnology (2020): 50-56
Authors: Jin, Wei and Madan, Bharat and Mussman, Brooklyn K and Hailemariam, Amen T and Fahad, Ahmed S and Wolfe, Jacy R and Kwon, Young Do and Zhang, Baoshan and Shapiro, Lawrence and Kwong, Peter D and DeKosky, Brandon J
Journal: Journal of biotechnology (2020): 50-56
Visualizing and Manipulating Biological Processes by Using HaloTag and SNAP-Tag Technologies.
Authors: Hoelzel, Conner A and Zhang, Xin
Journal: Chembiochem : a European journal of chemical biology (2020): 1935-1946
Authors: Hoelzel, Conner A and Zhang, Xin
Journal: Chembiochem : a European journal of chemical biology (2020): 1935-1946
[Combined application of SNAP-tag and fluorescence technique in in-situ protein analysis].
Authors: Qiao, Qinglong and Zhou, Wei and Chen, Jie and Liu, Wenjuan and Miao, Lu and Yin, Wenting and Xu, Zhaochao
Journal: Se pu = Chinese journal of chromatography (2019): 872-877
Authors: Qiao, Qinglong and Zhou, Wei and Chen, Jie and Liu, Wenjuan and Miao, Lu and Yin, Wenting and Xu, Zhaochao
Journal: Se pu = Chinese journal of chromatography (2019): 872-877
A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede.
Authors: Jung, Kwan Ho and Fares, Matthew and Grainger, Leeann S and Wolstenholme, Charles H and Hou, Anna and Liu, Yu and Zhang, Xin
Journal: Organic & biomolecular chemistry (2019): 1906-1915
Authors: Jung, Kwan Ho and Fares, Matthew and Grainger, Leeann S and Wolstenholme, Charles H and Hou, Anna and Liu, Yu and Zhang, Xin
Journal: Organic & biomolecular chemistry (2019): 1906-1915
One-step site-specific antibody fragment auto-conjugation using SNAP-tag technology.
Authors: Hussain, Ahmad Fawzi and Heppenstall, Paul A and Kampmeier, Florian and Meinhold-Heerlein, Ivo and Barth, Stefan
Journal: Nature protocols (2019): 3101-3125
Authors: Hussain, Ahmad Fawzi and Heppenstall, Paul A and Kampmeier, Florian and Meinhold-Heerlein, Ivo and Barth, Stefan
Journal: Nature protocols (2019): 3101-3125
Applications of SNAP-tag technology in skin cancer therapy.
Authors: Padayachee, Eden Rebecca and Adeola, Henry Ademola and Van Wyk, Jennifer Catherine and Nsole Biteghe, Fleury Augustine and Chetty, Shivan and Khumalo, Nonhlanhla Patience and Barth, Stefan
Journal: Health science reports (2019): e103
Authors: Padayachee, Eden Rebecca and Adeola, Henry Ademola and Van Wyk, Jennifer Catherine and Nsole Biteghe, Fleury Augustine and Chetty, Shivan and Khumalo, Nonhlanhla Patience and Barth, Stefan
Journal: Health science reports (2019): e103
Beyond O6-Benzylguanine: O6-(5-Pyridylmethyl)guanine as a Substrate for the Self-Labeling Enzyme SNAP-Tag.
Authors: Macias-Contreras, Miguel and He, Huan and Zhu, Lei
Journal: Bioconjugate chemistry (2018): 4104-4109
Authors: Macias-Contreras, Miguel and He, Huan and Zhu, Lei
Journal: Bioconjugate chemistry (2018): 4104-4109
Imaging Newly Synthesized and Old Histone Variant Dynamics Dependent on Chaperones Using the SNAP-Tag System.
Authors: Torné, Júlia and Orsi, Guillermo A and Ray-Gallet, Dominique and Almouzni, Geneviève
Journal: Methods in molecular biology (Clifton, N.J.) (2018): 207-221
Authors: Torné, Júlia and Orsi, Guillermo A and Ray-Gallet, Dominique and Almouzni, Geneviève
Journal: Methods in molecular biology (Clifton, N.J.) (2018): 207-221
SNAP-Tag-Based Subcellular Protein Labeling and Fluorescent Imaging with Naphthalimides.
Authors: Wang, Chao and Song, Xinbo and Xiao, Yi
Journal: Chembiochem : a European journal of chemical biology (2017): 1762-1769
Authors: Wang, Chao and Song, Xinbo and Xiao, Yi
Journal: Chembiochem : a European journal of chemical biology (2017): 1762-1769
Application notes
A New Protein Crosslinking Method for Labeling and Modifying Antibodies
Abbreviation of Common Chemical Compounds Related to Peptides
Bright Tide Fluor™-Based Fluorescent Peptides and Their Applications In Drug Discovery and Disease Diagnosis
FITC (Fluorescein isothiocyanate)
Fluorescein isothiocyanate (FITC)
Abbreviation of Common Chemical Compounds Related to Peptides
Bright Tide Fluor™-Based Fluorescent Peptides and Their Applications In Drug Discovery and Disease Diagnosis
FITC (Fluorescein isothiocyanate)
Fluorescein isothiocyanate (FITC)