Biotin Alkyne *CAS 773888-45-2*

Biotin Alkyne

CAS 773888-45-2

Biotin and biotin derivatives bind with high affinity to both avidins and streptavidins. Biotin alkyne can be readily conjugated to many biomolecules through the well-known click chemistry.

Chemical structure for Biotin Alkyne *CAS 1006592-45-5*

Protocol

SDS

COA

Catalog	Size	Price	Quantity
3021	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Biotin Alkyne *CAS 773888-45-2* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	355.404 µL	1.777 mL	3.554 mL	17.77 mL	35.54 mL
5 mM	71.081 µL	355.404 µL	710.808 µL	3.554 mL	7.108 mL
10 mM	35.54 µL	177.702 µL	355.404 µL	1.777 mL	3.554 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	281.37 g/mol	=	mL	x	mM	=	mmol

Citations

View all 4 citations: Citation Explorer

Development of a novel assay for antigen presentation measurement

Authors:

Li, Mei and Sharma, Falak Harshit and Chen, Yi-Ling and Araneda, Marco Esteban and Hammett, Amy and Miller, Derick and Pearce, Lilly and Chen, Kuan-Hui E

Journal:

Scientific Reports (2025): 33168

A low-cost, high-performance system for fluorescence lateral flow assays

Authors:

Lee, Linda G and Nordman, Eric S and Johnson, Martin D and Oldham, Mark F

Journal:

Biosensors (2013): 360--373

Implementation of P22 viral capsids as nanoplatforms

Authors:

Kang, Sebyung and Uchida, Masaki and O'Neil, Alison and Li, Rui and Prevelige, Peter E and Douglas, Trevor

Journal:

Biomacromolecules (2010): 2804--2809

Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields

Authors:

Morotomi-Yano, Keiko and Yano, Ken-ichi

Journal:

FEBS Open Bio

References

View all 78 references: Citation Explorer

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT((R)))

Authors:

Urbano N, Papi S, Ginanneschi M, De Santis R, Pace S, Lindstedt R, Ferrari L, Choi S, Paganelli G, Chinol M.

Journal:

Eur J Nucl Med Mol Imaging. (2006)

A biotin-protein bond with stability in plasma

Authors:

Bogusiewicz A, Mock NI, Mock DM.

Journal:

Anal Biochem (2005): 98

Probing the interaction of the biotin-avidin complex with the relaxivity of biotinylated Gd-DTPA

Authors:

Langereis S, Kooistra HA, van Genderen MH, Meijer EW.

Journal:

Org Biomol Chem (2004): 1271

Immunoassay of total prostate-specific antigen using europium(III) nanoparticle labels and streptavidin-biotin technology

Authors:

Huhtinen P, Soukka T, Lovgren T, Harma H.

Journal:

J Immunol Methods (2004): 111

Biotin is endogenously expressed in select regions of the rat central nervous system

Authors:

McKay BE, Molineux ML, Turner RW.

Journal:

J Comp Neurol (2004): 86

Physical properties

Molecular weight	281.37
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C)
UNSPSC	12352200
CAS	773888-45-2

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on October 20, 2025