Name: Biotin cadaverine
Brand: AAT Bioquest
SKU: 3004
Price: 115 USD
Availability: InStock

Biotin cadaverine

Biotin and biotin derivatives bind with high affinity to both avidins and streptavidins. Biotin and its derivatives can be conjugated to many biomolecules without significantly altering the biological activity of the target molecules since biotin is relatively a small molecule. A biopolymer (such as proteins) can react with several molecules of biotin that, in turn, can each bind one avidin. This characteristic greatly increases the sensitivity of many biological assays. Biotin derivatives are widely used for biological detections and purification. This biotin derivative is carbonyl-reactive. It is used for colorimetric assays for Factor XII (when used with EDC) and cellular transglutaminase. It is also widely used for labeling peptides (carboxylic acid groups) and nucleotides (5' phosphate groups) via the use of EDC.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
3004	25 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Biotin cadaverine to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	225.989 µL	1.13 mL	2.26 mL	11.299 mL	22.599 mL
5 mM	45.198 µL	225.989 µL	451.977 µL	2.26 mL	4.52 mL
10 mM	22.599 µL	112.994 µL	225.989 µL	1.13 mL	2.26 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	442.5 g/mol	=	mL	x	mM	=	mmol

Citations

View all 5 citations: Citation Explorer

Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine

Authors:

Biberoglu, Kevser and Schopfer, Lawrence M and Tacal, Ozden and Lockridge, Oksana

Journal:

Analytical Biochemistry (2020): 113718

Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields

Authors:

Morotomi-Yano, Keiko and Yano, Ken-ichi

Journal:

FEBS open bio (2017): 934--943

A low-cost, high-performance system for fluorescence lateral flow assays

Authors:

Lee, Linda G and Nordman, Eric S and Johnson, Martin D and Oldham, Mark F

Journal:

Biosensors (2013): 360--373

Implementation of P22 viral capsids as nanoplatforms

Authors:

Kang, Sebyung and Uchida, Masaki and O'Neil, Alison and Li, Rui and Prevelige, Peter E and Douglas, Trevor

Journal:

Biomacromolecules (2010): 2804--2809

Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields

Authors:

Morotomi-Yano, Keiko and Yano, Ken-ichi

Journal:

FEBS Open Bio

References

View all 78 references: Citation Explorer

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT((R)))

Authors:

Urbano N, Papi S, Ginanneschi M, De Santis R, Pace S, Lindstedt R, Ferrari L, Choi S, Paganelli G, Chinol M.

Journal:

Eur J Nucl Med Mol Imaging. (2006)

A biotin-protein bond with stability in plasma

Authors:

Bogusiewicz A, Mock NI, Mock DM.

Journal:

Anal Biochem (2005): 98

Probing the interaction of the biotin-avidin complex with the relaxivity of biotinylated Gd-DTPA

Authors:

Langereis S, Kooistra HA, van Genderen MH, Meijer EW.

Journal:

Org Biomol Chem (2004): 1271

Immunoassay of total prostate-specific antigen using europium(III) nanoparticle labels and streptavidin-biotin technology

Authors:

Huhtinen P, Soukka T, Lovgren T, Harma H.

Journal:

J Immunol Methods (2004): 111

Biotin is endogenously expressed in select regions of the rat central nervous system

Authors:

McKay BE, Molineux ML, Turner RW.

Journal:

J Comp Neurol (2004): 86

Physical properties

Molecular weight	442.50
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C)
UNSPSC	12352200

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Page updated on October 13, 2025