Name: BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]
Brand: AAT Bioquest
SKU: 23050
Price: 232 USD
Availability: InStock

BSB

(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene

BSB is a cell-permeable fluorescent probe that specifically binds to and labels intracellular beta-amyloid aggregates both in vitro (Ki = 400 nM) and in vivo. It is useful as an antemortem diagnostic tool for animal models of Alzheimer's disease.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
23050	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	207.775 µL	1.039 mL	2.078 mL	10.389 mL	20.777 mL
5 mM	41.555 µL	207.775 µL	415.55 µL	2.078 mL	4.155 mL
10 mM	20.777 µL	103.887 µL	207.775 µL	1.039 mL	2.078 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	481.29 g/mol	=	mL	x	mM	=	mmol

References

View all 50 references: Citation Explorer

Focus on Molecules: Rod cGMP Phosphodiesterase Type 6

Authors:

Ionita MA, Pittler SJ.

Journal:

Exp Eye Res (2007): 1

Translational regulation of the rod photoreceptor cGMP-phosphodiesterase: the role of the 5'- and 3'-untranslated regions

Authors:

Piri N, Mendoza E, Shih J, Yamashita CK, Akhmedov NB, Farber DB.

Journal:

Exp Eye Res (2006): 841

ANP-mediated cGMP signaling and phosphodiesterase inhibition in the rat cervical spinal cord

Authors:

de Vente J, Markerink-van Ittersum M, Vles JS.

Journal:

J Chem Neuroanat (2006): 263

Enhancing cGMP in experimental progressive renal fibrosis: soluble guanylate cyclase stimulation vs. phosphodiesterase inhibition

Authors:

Wang Y, Kramer S, Loof T, Martini S, Kron S, Kawachi H, Shimizu F, Neumayer HH, Peters H.

Journal:

Am J Physiol Renal Physiol (2006): F167

Inhibition of cGMP-dependent protein kinase by the regulatory subunit of photoreceptor cGMP phosphodiesterase

Authors:

Guo LW, Ruoho AE.

Journal:

Neurosci Lett (2006): 252

Physical properties

Molecular weight	481.29
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on October 25, 2025