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Cal-590L® Dextran Conjugate
MW 10,000
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Cells may be physically loaded with the cell-impermeant salt forms of these dextran-conjugated calcium indicators using patch pipette or microinjection. The fluorescence signal from these cells is measured using fluorescence microscopy. The dextran forms of our calcium indicators show a dramatic reduction in both leakage and compartmentalization compared to the AM ester forms. Among the fluorescent calcium indicator dextran conjugates, Cal-590L dextran conjugates might be a better choice than other red fluorescent dextran conjugates due to its higher fluorescence quantum yield and larger fluorescence enhancement by calcium. Cal-590L dextran has Kd ~230 uM.
Among the fluorescent calcium indicator dextran conjugates, Cal-590L dextran conjugates might be a better choice than other red fluorescent dextran conjugates due to its higher fluorescence quantum yield and larger fluorescence enhancement by calcium. Cal-590L dextran has Kd ~230 uM.
Among the fluorescent calcium indicator dextran conjugates, Cal-590L dextran conjugates might be a better choice than other red fluorescent dextran conjugates due to its higher fluorescence quantum yield and larger fluorescence enhancement by calcium. Cal-590L dextran has Kd ~230 uM.
protocol
Protocol
sds
SDS
COA
CatalogSize
Price
Quantity
205251 mg
Price
 
Physical properties
Molecular weightN/A
SolventWater
Spectral properties
Excitation (nm)569
Emission (nm)590
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
Documents
Protocol
Safety Data Sheet
Certificate of Analysis
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Page updated on October 18, 2025