Concanavalin A, XFD594 Labeled

XFD594 is manufactured by AAT Bioquest, and it has a chemical structure similar to that of Alexa Fluor® 594 (Alexa Fluor® is the trademark of Thermo Fisher). Concanavalin A (ConA) is a lectin that binds specifically to certain structures found in various sugars, glycoproteins and glycolipids. ConA is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells. ConA binds specifically α-D-mannosyl and α-D-glucosyl residues (two hexoses differing only in the alcohol on carbon 2) in terminal position of ramified structures from B-Glycans. Concanavalin A (Con A) is one of the most widely used lectins in cell biology. XFD594-labeled Concanavalin A (equivalent to Alexa Fluor® 594 conjugate of Con A, Alexa Fluor® is the trademark of Thermo Fisher) exhibits the bright, red fluorescence. XFD594 Con A selectively binds to a-mannopyranosyl and a-glucopyranosyl residues.

Datasheet

SDS

COA

Catalog	Size	Price	Quantity
25575	1 mg	Price

References

View all 50 references: Citation Explorer

ISFET and Dex-AgNPs based portable sensor for reusable and real-time determinations of concanavalin A and glucose on smartphone.

Authors:

Zhao, Shuang and Shi, Cong and Hu, Hongyang and Li, Zhengping and Xiao, Gang and Yang, Qiaochun and Sun, Peng and Cheng, Linyang and Niu, Wencheng and Bi, Jinshun and Yue, Zhao

Journal:

Biosensors & bioelectronics (2020): 111962

Montelukast ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting TNF-α/JNK signaling pathway.

Authors:

El-Kashef, Dalia H and Abdelrahman, Rehab S

Journal:

Toxicology and applied pharmacology (2020): 114931

Acupuncture stimulation attenuates TNF-α production via vagal modulation in the concanavalin A model of hepatitis.

Authors:

Lim, Hee-Don and Kim, Ki-Joong and Jo, Byung Gon and Park, Ji-Yeun and Namgung, Uk

Journal:

Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020): 964528420907338

Deficiency of O-linked-glycosylation regulates activation of T cells and aggravates Concanavalin A-induced liver injury.

Authors:

Hao, Xiaohua and Gao, Meixin and He, Lingling and Ye, Xiaohui and Yang, Junru and Zhang, Fuyang and Liu, Ran and Wei, Hongshan

Journal:

Toxicology (2020): 152411

Nicotine attenuates concanavalin A-induced liver injury in mice by regulating the α7-nicotinic acetylcholine receptor in Kupffer cells.

Authors:

Zhao, Jing and Park, Surim and Kim, Jong-Won and Qi, Jing and Zhou, Zixiong and Lim, Chae Woong and Kim, Bumseok

Journal:

International immunopharmacology (2020): 106071

Physical properties

Molecular weight	N/A
Solvent	Water

Spectral properties

Absorbance (nm)	592
Correction factor (260 nm)	0.43
Correction factor (280 nm)	0.56
Extinction coefficient (cm ^-1 M ^-1)	92000
Excitation (nm)	590
Emission (nm)	618
Quantum yield	0.66 ¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Instrument settings

Fluorescence microscope
Excitation	Cy3/TRITC filter set
Emission	Cy3/TRITC filter set
Recommended plate	Black wall/clear bottom

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Page updated on April 21, 2026