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Congo Red NHS Ester

Congo Red has been used as a common qualitative staining method for the identification of amyloids in vitro and in tissue sections. Congo Red NHS ester is an excellent building block to develop Congo Red-based amyloid probes. The investigation of the amyloid formation is currently one of the most important tasks in the neurological field. Research in this area involves not only understanding how amyloidosis develops and how to prevent amyloid plaque formation but also investigating functional amyloids. In amyloidosis diseases, amyloids can be detected in the kidney, liver, brain and other human and animal organs. The development of neurodegenerative human diseases, such as Alzheimer’s disease and Parkinson’s disease, is probably the consequence of accumulation of insoluble amyloid plaques in the nerve tissue.

Spectrum

References

View all 50 references: Citation Explorer
Fine-needle aspiration of amyloidoma: A critical analysis.
Authors: Ramani, Nisha S and Krishnan, Bhuvaneswari
Journal: Cancer cytopathology (2024): 179-185
Localized Urinary Bladder Amyloidosis as Urothelial Cancer Mimicker.
Authors: Regmi, Aayushma and Mehta, Maitri and Farooq, Ahmer V and Turk, Thomas M and Wojcik, Eva M and Picken, Maria M
Journal: Archives of pathology & laboratory medicine (2024)
Unilateral Granular Type 2 Corneal Dystrophy With Exacerbation After LASIK.
Authors: Bostan, Cristina and Randleman, J Bradley
Journal: Cornea (2024): 648-651
A case of AA amyloidosis complicated by proliferating pilomatricoma and a review of the literature.
Authors: Obara, Koya and Amoh, Yasuyuki
Journal: The Journal of dermatology (2024)
ALECT2 amyloidosis with concurrent IgG4-related interstitial nephritis, membranous nephropathy and diabetic kidney disease: a case report and literature review.
Authors: Shaheen, Muhammad and Bharat, Anchit and Friedman, Allon N and Guo, Shunhua
Journal: Journal of nephrology (2024)
Page updated on December 11, 2024

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Catalog Number23069
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Physical properties

Molecular weight

1039.19

Solvent

DMSO

Spectral properties

Absorbance (nm)

195

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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