Name: Cyanine 3 maleimide [equivalent to Cy3® maleimide]
Brand: AAT Bioquest
SKU: 142
Price: 115 USD
Availability: InStock

Cyanine 3 maleimide

equivalent to Cy3® maleimide

A variety of cyanine 3 (Cy3®) dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc. Cy3® dyes have enhanced fluorescence upon binding to proteins. Cy3® maleimide readily reacts with thiol groups. Cy3® is the trademark of GE Healthcare.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
142	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Cyanine 3 maleimide [equivalent to Cy3® maleimide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	115.351 µL	576.754 µL	1.154 mL	5.768 mL	11.535 mL
5 mM	23.07 µL	115.351 µL	230.702 µL	1.154 mL	2.307 mL
10 mM	11.535 µL	57.675 µL	115.351 µL	576.754 µL	1.154 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	866.92 g/mol	=	mL	x	mM	=	mmol

Citations

View all 18 citations: Citation Explorer

ATP promotes protein coacervation through conformational compaction

Authors:

Zhu, Yueling and Lin, Shiyan and Meng, Lingshen and Sun, Min and Liu, Maili and Li, Jingyuan and Tang, Chun and Gong, Zhou

Journal:

Journal of Molecular Cell Biology (2024): mjae038

Competitive binding-mediated mesoscale protein-protein interactions direct microtubule growth

Authors:

Wei, Zhiyi and Jia, Xuanyan and Lin, Leishu and Guo, Siqi and Zhou, Lulu and Jin, Gaowei and Dong, Jiayuan and Xiao, Jinman and Xie, Xingqiao and Li, Yiming and others,

Conformational compaction as a mechanism for ATP resolubilization of protein condensates

Authors:

Gong, Zhou and Zhu, Yueling and Lin, Shiyan and Meng, Ling-Shen and Sun, Min and Liu, Maili and Li, Jingyuan and Tang, Chun

Spatiotemporal stop-and-go dynamics of the mitochondrial TOM core complex correlates with channel activity

Authors:

Wang, Shuo and Findeisen, Lukas and Leptihn, Sebastian and Wallace, Mark I and H{\"o}rning, Marcel and Nussberger, Stephan

Journal:

Communications biology (2022): 1--11

Caveat fluorophore: an insiders’ guide to small-molecule fluorescent labels

Authors:

Grimm, Jonathan B and Lavis, Luke D

Journal:

Nature methods (2022): 149--158

References

View all 21 references: Citation Explorer

Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy

Authors:

Wiessler M, Hennrich U, Pipkorn R, Waldeck W, Cao L, Peter J, Ehemann V, Semmler W, Lammers T, Braun K.

Journal:

Theranostics (2011): 381

Excitation of Cy5 in self-assembled lipid bilayers using optical microresonators

Authors:

Freeman LM, Li S, Dayani Y, Choi HS, Malmstadt N, Armani AM.

Journal:

Appl Phys Lett (2011): 143703

Rational approach to select small peptide molecular probes labeled with fluorescent cyanine dyes for in vivo optical imaging

Authors:

Berezin MY, Guo K, Akers W, Livingston J, Solomon M, Lee H, Liang K, Agee A, Achilefu S.

Journal:

Biochemistry (2011): 2691

In vivo detection of embryonic stem cell-derived cardiovascular progenitor cells using Cy3-labeled Gadofluorine M in murine myocardium

Authors:

Adler ED, Bystrup A, Briley-Saebo KC, Mani V, Young W, Giovanonne S, Altman P, Kattman SJ, Frank JA, Weinmann HJ, Keller GM, Fayad ZA.

Journal:

JACC Cardiovasc Imaging (2009): 1114

Quantitative proteomics by fluorescent labeling of cysteine residues using a set of two cyanine-based or three rhodamine-based dyes

Authors:

Volke D, Hoffmann R.

Journal:

Electrophoresis (2008): 4516

Physical properties

Molecular weight	866.92
Solvent	DMSO

Spectral properties

Correction factor (260 nm)	0.07
Correction factor (280 nm)	0.073
Extinction coefficient (cm ^-1 M ^-1)	150000 ¹
Excitation (nm)	555
Emission (nm)	569
Quantum yield	0.15 ¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on September 22, 2025