ddGTP [2',3'-Dideoxyguanosine-5'-triphosphate] *10 mM in ddH2O*

ddGTP

2',3'-Dideoxyguanosine-5'-triphosphate; 10 mM in ddH2O

Sanger sequencing, also known as the chain termination method, is a technique for DNA sequencing based upon the selective incorporation of chain-terminating dideoxynucleotides (ddNTPs) by DNA polymerase. It was developed by Frederick Sanger and colleagues in 1977. Although the newer NGS technologies are becoming common in clinical research labs due to their higher throughput capabilities and lower costs per sample, Sanger sequencing with 99.99% accuracy is still the “gold standard” for clinical research sequencing. dd-GTP is one of the four critical ddNTP components for performing Sanger sequencing.

Chemical structure for ddGTP [2',3'-Dideoxyguanosine-5'-triphosphate].

Protocol

SDS

COA

Catalog	Size	Price	Quantity
17210	1 umole	Price

References

View all 4 references: Citation Explorer

Detection and genotyping of human papillomavirus DNA in cervical cancer tissues with fluorescence polarization.

Authors:

Gao, Yan-E and Zhang, Ju and Wu, Jing and Chen, Zhong-Can and Yan, Xiao-Jun

Journal:

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica (2003): 1029-34

Microcapillary reactors using solid-phase DNA sequencing for direct sample introduction into slab gels.

Authors:

Xu, Y and Bruch, R C and Soper, S A

Journal:

BioTechniques (2000): 904-8, 910, 912

Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase.

Authors:

Prasad, V R and Lowy, I and de los Santos, T and Chiang, L and Goff, S P

Journal:

Proceedings of the National Academy of Sciences of the United States of America (1991): 11363-7

Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition.

Authors:

Reardon, J E

Journal:

The Journal of biological chemistry (1989): 19039-44

Physical properties

Molecular weight	491.18
Solvent	Water

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on October 27, 2025