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Diazepam BSA Conjugate

Product key features

  • Increased Immunogenicity: Covalent attachment of diazepam to BSA enhances antigen presentation and facilitates robust antibody production.
  • Structural Integrity Maintained: Conjugation preserves the active pharmacophore of diazepam, ensuring selective antibody generation and recognition.
  • High Epitope Density: Multiple diazepam molecules conjugated per BSA molecule enable improved assay sensitivity and reproducibility.
  • Broad Utility: Optimized for use as an immunogen or coating antigen in competitive ELISA, lateral flow assays, and other immunodetection platforms.

Product description

Diazepam BSA Conjugate is a bioconjugate in which diazepam is covalently linked to bovine serum albumin (BSA) to enhance its immunogenicity for use in immunoassay development. The conjugation is typically performed via active ester or linker-mediated chemistry to maintain the structural integrity of the diazepam pharmacophore while achieving efficient and stable attachment to the carrier protein. This conjugate is commonly employed as an immunogen for generating diazepam-specific polyclonal and monoclonal antibodies, as well as a coating antigen in competitive ELISA, lateral flow assays, and other immunodetection platforms. The high antigen density on BSA improves assay sensitivity and specificity, facilitating the reliable detection of diazepam and structurally related benzodiazepines in biological samples. This reagent is intended for research use only and is not approved for diagnostic or therapeutic applications.

References

View all 50 references: Citation Explorer
GABALAGEN Facilitates Pentobarbital-Induced Sleep by Modulating the Serotonergic System in Rats.
Authors: Ye, Minsook and Rheu, Kyoung-Min and Lee, Bae-Jin and Shim, Insop
Journal: Current issues in molecular biology (2024): 11176-11189
Effect of prednisolone in a kindling model of epileptic seizures in rats on cytokine and intestinal microbiota diversity.
Authors: de Lima, Amanda Muliterno Domingues Lourenço and de Lima Rosa, Gabriel and Guzzo, Edson Fernando Müller and Padilha, Rafael Bremm and de Araujo, Milena Conci and da Silva, Rodrigo Costa and Coitinho, Adriana Simon and Van Der Sand, Sueli Teresinha
Journal: Epilepsy & behavior : E&B (2024): 109800
Ivermectin Exerts Anticonvulsant Effects Against Status Epilepticus Induced by Lithium-Pilocarpine in Rats via GABAA Receptor and Neuroinflammation Modulation: Possible Interaction of Opioidergic Pathways and KATP Channel with Nitrergic System.
Authors: Manavi, Mohammad Amin and Toutounchian, Samaneh and Afsahi, Sahar and Ebrahim Soltani, Zahra and Mohammad Jafari, Razieh and Dehpour, Ahmad Reza
Journal: Molecular neurobiology (2024): 7627-7638
Evaluation of repeated ghrelin administration on seizures, oxidative stress and neurochemical parameters in pentyleneterazole induced kindling in rats.
Authors: Ergul Erkec, Ozlem and Yunusoglu, Oruc and Huyut, Zubeyir
Journal: The International journal of neuroscience (2024): 420-428
5,7,3',4',5'-Pentamethoxyflavone, a Flavonoid Monomer Extracted From Murraya paniculata (L.) Jack, Alleviates Anxiety Through the A2AR/Gephyrin/GABRA2 Pathway.
Authors: Ma, Wenli and Sui, Dayun and Sun, Weilun and Yu, Ping and Li, Yuangeng and Guo, Meiqi and Wang, Huifeng and Zhang, Xiaoze and Yu, Xiaofeng and Fu, Wenwen and Xu, Huali
Journal: Phytotherapy research : PTR (2024): 5539-5548
Page updated on August 11, 2025

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Catalog Number50665
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Physical properties

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure