DNP-PEG4 acid

Compared to the commonly used DNP-X acid (#2020), DNP-PEG4 acid has much better water solubility. It is an excellent amine-reactive building block for developing a probe that can be recognized by anti-DNP antibodies. It might be also used as an excellent amine-reactive FRET quencher paired with Trp or Tyr. Its terminal carboxy group readily reacts with primary amines in the presence of EDC and DCC to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
2022	25 mg	Price

References

View all 50 references: Citation Explorer

Nano-Snowflower of Gold Nanoparticles-Ruthenium Metallopolymer-Carbon Nanotubes Binding Anti-DNP IgE Antibody.

Authors:

Li, Huayang and Wu, Jie and Melnyczuk, John M and Olubi, Omotunde and Lewis, Lauchon I and Cao, Yang and Nagappan, Peri and Khan, Shafiq A and Ingram, Conrad W and Harruna, Issifu I

Journal:

Journal of nanoscience and nanotechnology (2015): 5733-40

Peptide mimics of hapten DNP: the effect of affinity of anti-DNP monoclonal antibodies for the selection of phage-displayed mimotopes.

Authors:

Kalaycioglu, Atila T and Russell, Peter H and Howard, Colin R

Journal:

Journal of immunological methods (2011): 36-42

Generation of heterogeneous rabbit anti-DNP antibodies by gene conversion and hypermutation of rearranged VL and VH genes during clonal expansion of B cells in splenic germinal centers.

Authors:

Sehgal, D and Schiaffella, E and Anderson, A O and Mage, R G

Journal:

European journal of immunology (2000): 3634-44

Determination of the binding of ligands containing the N-2,4-dinitrophenyl group to bivalent monoclonal rat anti-DNP antibody using affinity capillary electrophoresis.

Authors:

Mammen, M and Gomez, F A and Whitesides, G M

Journal:

Analytical chemistry (1995): 3526-35

Fast solid support detection of human papillomavirus in in vitro amplified DNA using a DNP-anti DNP monoclonal antibody couple.

Authors:

Baccard-Longère, M and Alpha-Bazin, B and Chypre, C and Sauvaigo, S and Téoule, R and Bernard, P and Seigneurin, J M

Journal:

Journal of virological methods (1994): 29-38

Physical properties

Molecular weight	431.40
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	858126-76-8

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on November 2, 2025