Name: EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]
Brand: AAT Bioquest
SKU: 611
Price: 934 USD
Availability: InStock

EDANS acid

5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid

EDANS is one of the most popular donors for developing FRET-based nucleic acid probes (such as Molecular Beacons) and protease substrates. EDANS is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
611	10 g	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	375.488 µL	1.877 mL	3.755 mL	18.774 mL	37.549 mL
5 mM	75.098 µL	375.488 µL	750.976 µL	3.755 mL	7.51 mL
10 mM	37.549 µL	187.744 µL	375.488 µL	1.877 mL	3.755 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	266.32 g/mol	=	mL	x	mM	=	mmol

References

View all 54 references: Citation Explorer

The beta4-beta8 Groove Is an ATP-interactive Site in the alpha Crystallin Core Domain of the Small Heat Shock Protein, Human alphaB Crystallin

Authors:

Ghosh JG, Houck SA, Doneanu CE, Clark JI.

Journal:

J Mol Biol (2006): 364

Recombinant expression and partial characterization of an active soluble histo-aspartic protease from Plasmodium falciparum

Authors:

Xiao H, Sinkovits AF, Bryksa BC, Ogawa M, Yada RY.

Journal:

Protein Expr Purif (2006): 88

Internally quenched peptides for the study of lysostaphin: An antimicrobial protease that kills Staphylococcus aureus

Authors:

Warfield R, Bardelang P, Saunders H, Chan WC, Penfold C, James R, Thomas NR.

Journal:

Org Biomol Chem (2006): 3626

A quenched fluorescent dipeptide for assaying dispase- and thermolysin-like proteases

Authors:

Weimer S, Oertel K, Fuchsbauer HL.

Journal:

Anal Biochem (2006): 110

Characterization and inhibition of SARS-coronavirus main protease

Authors:

Liang PH., undefined

Journal:

Curr Top Med Chem (2006): 361

Physical properties

Molecular weight	266.32
Solvent	DMSO

Spectral properties

Correction factor (280 nm)	0.107
Extinction coefficient (cm ^-1 M ^-1)	5900
Excitation (nm)	336
Emission (nm)	455

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	50402-56-7

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Page updated on October 13, 2025