EDANS C5 maleimide

Name: EDANS C5 maleimide
Brand: AAT Bioquest
SKU: 619
Price: 105 USD
Availability: InStock

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Safety data sheet

Product protocol

Certificate of analysis

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Digital PCR

Polymerase Chain Reaction (PCR)

Real-Time PCR (qPCR)

Reverse Transcription PCR (RT-PCR)

RNA Purification & Analysis

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Application notes

A Novel Fluorescent Probe for Imaging and Detecting Hydroxyl Radical in Living Cells

Abbreviation of Common Chemical Compounds Related to Peptides

Annexin V

Bright Tide Fluor™-Based Fluorescent Peptides and Their Applications In Drug Discovery and Disease Diagnosis

Calcein

AssayWise

Glycerol 3-Phosphate Assays

Nucleic Acid Quantification

Hydroxyl Radical Detection

Thiol Detection

Nucleic Acid Detection, Quantification and Imaging

EDANS is one of the most popular donors for developing FRET-based nucleic acid probes (such as Molecular Beacons) and protease substrates. EDANS is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive. EDANS C5 maleimide is a thiol-reactive EDANS derivative. It is water-soluble, and has the same spectral properties with EDANS.

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Catalog Number	619
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Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
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Physical properties

Molecular weight	417.44
Solvent	DMSO

Spectral properties

Correction Factor (280 nm)	0.107
Extinction coefficient (cm ^-1 M ^-1)	5900
Excitation (nm)	336
Emission (nm)	455

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Spectrum

Open in Advanced Spectrum Viewer

Product family

Name	Excitation (nm)	Emission (nm)	Extinction coefficient (cm ^-1 M ^-1)	Quantum yield	Correction Factor (280 nm)	Correction Factor (260 nm)
EDANS C2 maleimide	336	455	5900	-	0.107	-
XFD488 C5 Maleimide Same Structure to Alexa Fluor™ 488 C5 Maleimide	499	520	71000	0.92¹	0.11	0.30
XFD350 C5 Maleimide Same Structure to Alexa Fluor™ 350 C5 Maleimide	343	441	19000	-	0.19	0.25
XFD532 C5 Maleimide Same Structure to Alexa Fluor™ 532 C5 Maleimide	534	553	81000	0.61¹	0.09	0.24
XFD594 C5 Maleimide Same Structure to Alexa Fluor™ 594 C5 Maleimide	590	618	90000	0.66¹	0.56	0.43

References

View all 3 references: Citation Explorer

Synthesis and evaluation of fluorogenic triglycerides as lipase assay substrates.
Authors: Andersen, Rokhsana J and Brask, Jesper
Journal: Chemistry and physics of lipids (2016): 72-9

FRET-Protease-Coupled Peptidyl-Prolyl cis-trans Isomerase Assay: New Internally Quenched Fluorogenic Substrates for High-Throughput Screening.
Authors: Caporale, Andrea and Mascanzoni, Fabiola and Farina, Biancamaria and Sturlese, Mattia and Di Sorbo, Gianluigi and Fattorusso, Roberto and Ruvo, Menotti and Doti, Nunzianna
Journal: Journal of biomolecular screening (2016): 701-12

Characterization and inhibition of SARS-coronavirus main protease.
Authors: Liang, Po-Huang
Journal: Current topics in medicinal chemistry (2006): 361-76

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