EDANS iodoacetamide [5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid]

EDANS iodoacetamide

5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid

EDANS iodoacetamide [5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid] is a thiol-reactive EDANS derivative. It is water-soluble, and has the same spectral properties with EDANS.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
618	25 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of EDANS iodoacetamide [5-((((2-Iodoacetyl)amino)ethyl)amino)naphthalene-1-sulfonic acid] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	230.282 µL	1.151 mL	2.303 mL	11.514 mL	23.028 mL
5 mM	46.056 µL	230.282 µL	460.564 µL	2.303 mL	4.606 mL
10 mM	23.028 µL	115.141 µL	230.282 µL	1.151 mL	2.303 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	434.25 g/mol	=	mL	x	mM	=	mmol

References

View all 54 references: Citation Explorer

The beta4-beta8 Groove Is an ATP-interactive Site in the alpha Crystallin Core Domain of the Small Heat Shock Protein, Human alphaB Crystallin

Authors:

Ghosh JG, Houck SA, Doneanu CE, Clark JI.

Journal:

J Mol Biol (2006): 364

Recombinant expression and partial characterization of an active soluble histo-aspartic protease from Plasmodium falciparum

Authors:

Xiao H, Sinkovits AF, Bryksa BC, Ogawa M, Yada RY.

Journal:

Protein Expr Purif (2006): 88

Internally quenched peptides for the study of lysostaphin: An antimicrobial protease that kills Staphylococcus aureus

Authors:

Warfield R, Bardelang P, Saunders H, Chan WC, Penfold C, James R, Thomas NR.

Journal:

Org Biomol Chem (2006): 3626

A quenched fluorescent dipeptide for assaying dispase- and thermolysin-like proteases

Authors:

Weimer S, Oertel K, Fuchsbauer HL.

Journal:

Anal Biochem (2006): 110

Characterization and inhibition of SARS-coronavirus main protease

Authors:

Liang PH., undefined

Journal:

Curr Top Med Chem (2006): 361

Physical properties

Molecular weight	434.25
Solvent	DMSO

Spectral properties

Correction factor (280 nm)	0.107
Extinction coefficient (cm ^-1 M ^-1)	5900
Excitation (nm)	336
Emission (nm)	455

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on July 26, 2023