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EDTA Alkyne

Product key features

  • A unique EDTA building block
  • Mild reaction conditions
  • High reaction yield

Product description

EDTA alkyne is an excellent building block to develop site-specific ethylenediaminetetraacetic acid (EDTA) probes for variety of biomedical applications. It readily reacts with an azido compound (such as DBCO) under the well-known click chemistry conditions. EDTA is the most commonly used chelator for complexing transitional metal ions. EDTA chelation therapy uses the chelating agent, EDTA, to remove heavy metals and minerals from the body. It involves injecting EDTA into the bloodstream, where it binds to these substances, allowing them to be excreted through urine. EDTA is approved for treating lead poisoning, but it's also used in other conditions, including coronary artery disease and arthritis. 

References

View all 50 references: Citation Explorer
Two-in-one strategy to enhance the stability of Ti3C2Tx in transition metal ion solutions.
Authors: Wang, Jie and Xie, Guanshun and Zhang, Senlin and Li, Guohao and Huang, Zhaohui and Li, Xiaohui and Xie, Xiuqiang and Zhang, Nan
Journal: Journal of colloid and interface science (2025): 724-732
Use of confocal laser scanning microscopy to evaluate the metal ion removal and destabilization of Enterococcus faecalis biofilms by EDTA and etidronic acid.
Authors: Tartari, Talita and Estrela, Carlos and de Araújo, Larissa Barbosa Borges and Graeff, Márcia Sirlene Zardin and de Andrade, Flaviana Bombarda and Duarte, Marco Antonio Hungaro
Journal: Odontology (2025)
Highly efficient determination of metal ion in cosmetic samples by reversed-phase liquid-liquid microextraction based on green hydrophobic deep eutectic solvent.
Authors: Liu, Bangfu and Zhou, Le-Zhou and He, Guo-Wen and Wang, Chaoli
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry (2024): 115-121
Preparation of cellulose nanofiber/polyvinyl alcohol-based composite films for metal ion detection by starch/disodium calcium ethylenediaminetetraacetate synergistic complexation effect.
Authors: Wang, Can and Shang, Yanlong and Guan, Jie and Chen, Nannan and Gao, Shan and Xu, Wenjing and Tao, Limin and Li, Zhimao and Shao, Ziqiang
Journal: International journal of biological macromolecules (2024): 137265
Luminescent Silicon Nanocrystals as Metal Ion Sensors.
Authors: Stacy, Benjamin J and Nagasaki, Kara and Korgel, Brian A
Journal: ACS nano (2024): 15744-15753
Page updated on June 28, 2025

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Catalog Number65008
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Physical properties

Molecular weight

636.62

Solvent

DMF

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure