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EDTA Maleimide

Product key features

  • A unique EDTA building block
  • Mild reaction conditions
  • High reaction yield

Product description

EDTA maleimide is an excellent building block to develop site-specific ethylenediaminetetraacetic acid (EDTA) probes for variety of biomedical applications. It readily reacts with a thiol compound under extremely mild conditions. EDTA is the most commonly used chelator for complexing transitional metal ions. EDTA chelation therapy uses the chelating agent, EDTA, to remove heavy metals and minerals from the body. It involves injecting EDTA into the bloodstream, where it binds to these substances, allowing them to be excreted through urine. EDTA is approved for treating lead poisoning, but it's also used in other conditions, including coronary artery disease and arthritis.

References

View all 50 references: Citation Explorer
Season-based phytoremediation potential of brown mustard for lead decontamination: effect of EDTA chelation and antioxidant enzyme activity.
Authors: Chen, Deqiang and Ibrahim, Muhammad and Soroma, Mara and Danjaji, Hafsat Alhassan and Jibo, Adam Umar and Yang, Ying
Journal: International journal of phytoremediation (2025): 1-13
Combined Topography-Guided Trans-Epithelial PRK and PTK for Treatment of Calcific Band Keratopathy Unresponsive to EDTA Chelation Therapy.
Authors: Passidomo, Fedele and Addabbo, Giuseppe and Pignatelli, Francesco and Niro, Alfredo and Buonamassa, Rosa
Journal: International medical case reports journal (2025): 187-194
Severe Descemetocele after EDTA Chelation for Band Keratopathy.
Authors: Montolío-Marzo, Santiago and Rodríguez-Iranzo, Guillermo and Peris-Martínez, Cristina
Journal: Ophthalmology (2024): 395
Excimer laser-assisted phototherapeutic keratectomies combined to EDTA chelation for the treatment of calcific band keratopathy.
Authors: Spadea, Leopoldo and Giannico, Maria Ilaria and Iannaccone, Andrea and Pistella, Santino
Journal: European journal of ophthalmology (2022): NP42-NP46
SARS-CoV-2 attachment to host cells is possibly mediated via RGD-integrin interaction in a calcium-dependent manner and suggests pulmonary EDTA chelation therapy as a novel treatment for COVID 19.
Authors: Dakal, Tikam Chand
Journal: Immunobiology (2021): 152021
Page updated on June 29, 2025

Ordering information

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Catalog Number65006
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Additional ordering information

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Physical properties

Molecular weight

690.66

Solvent

DMF

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure