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Estradiol maleimide

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Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Physical properties
Molecular weight481.55
SolventDMSO
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
Alternative formats
Estradiol succinimidyl ester

OverviewpdfSDSpdfProtocol


Molecular weight
481.55
Estradiol is an estrogen steroid hormone and the major female sex hormone. It is also called 17 beta-estradiol. Estradiol is involved in the regulation of the estrous and menstrual female reproductive cycles. It is responsible for the development of female secondary sexual characteristics and important in the development and maintenance of female reproductive tissues and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower compared to those in females, estradiol has important roles in males as well. An estradiol test measures the amount of the hormone estradiol in your blood. It is also called an E2 test. An estradiol test has a number of clinically important applications. Estradiol maleimide is a convenient building block for developing estradiol conjugates and assays.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Estradiol maleimide to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM207.663 µL1.038 mL2.077 mL10.383 mL20.766 mL
5 mM41.533 µL207.663 µL415.326 µL2.077 mL4.153 mL
10 mM20.766 µL103.831 µL207.663 µL1.038 mL2.077 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles
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References


View all 50 references: Citation Explorer
Estradiol valerate in COC has more favorable inflammatory profile than synthetic ethinyl estradiol - a randomized trial.
Authors: Kangasniemi, Marika H and Haverinen, Annina and Luiro, Kaisu and Hiltunen, J Kalervo and Komsi, Elina K and Arffman, Riikka K and Heikinheimo, Oskari and Tapanainen, Juha S and Piltonen, Terhi T
Journal: The Journal of clinical endocrinology and metabolism (2020)
Degradation of 17β-estradiol by Novosphingobium sp. ES2-1 in aqueous solution contaminated with tetracyclines.
Authors: Li, Shunyao and Liu, Juan and Sun, Kai and Yang, Zhiyao and Ling, Wanting
Journal: Environmental pollution (Barking, Essex : 1987) (2020): 114063
Advanced oxidative processes in the degradation of 17β-estradiol present on surface waters: kinetics, byproducts and ecotoxicity.
Authors: Perondi, Taise and Michelon, William and Junior, Paulo Reis and Knoblauch, Priscila M and Chiareloto, Marilete and de Fátima Peralta Muniz Moreira, Regina and Peralta, Rosely Aparecida and Düsman, Elisângela and Pokrywiecki, Ticiane Sauer
Journal: Environmental science and pollution research international (2020)
Changes in serum estradiol levels with Estring in postmenopausal women with breast cancer treated with aromatase inhibitors.
Authors: Streff, Alyssa and Chu-Pilli, Michele and Stopeck, Alison and Chalasani, Pavani
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)
A self-powered photoelectrochemical cathodic aptasensor for the detection of 17β-estradiol based on FeOOH/In2S3 photoanode.
Authors: Li, Yuewen and Liu, Lei and Feng, Jinhui and Ren, Xiang and Zhang, Yong and Yan, Tao and Liu, Xuejing and Wei, Qin
Journal: Biosensors & bioelectronics (2020): 112089
Skeletal impact of 17β-estradiol in T cell-deficient mice: age-dependent bone effects and osteosarcoma formation.
Authors: Cheng, Julia N and Frye, Jennifer B and Whitman, Susan A and Funk, Janet L
Journal: Clinical & experimental metastasis (2020): 269-281
Spatio-temporal distribution and transformation of 17α- and 17β-estradiol in sterilized soil: A column experiment.
Authors: Yu, Weiwei and Du, Banghao and Fan, Gongduan and Yang, Shuo and Yang, Lun and Zhang, Minne
Journal: Journal of hazardous materials (2020): 122092
The Effect of Perimenopausal Transdermal Estradiol and Micronized Progesterone on Markers of Risk for Arterial Disease.
Authors: Gordon, Jennifer L and Rubinow, David R and Watkins, Lana and Hinderliter, Alan L and Caughey, Melissa C and Girdler, Susan S
Journal: The Journal of clinical endocrinology and metabolism (2020)
Atogepant Has No Clinically Relevant Effects on the Pharmacokinetics of an Ethinyl Estradiol/Levonorgestrel Oral Contraceptive in Healthy Female Participants.
Authors: Ankrom, Wendy and Xu, Jialin and Vallee, Marie-Helene and Dockendorf, Marissa F and Armas, Danielle and Boinpally, Ramesh and Min, K Chris
Journal: Journal of clinical pharmacology (2020)
Immune modulating effects of additional supplementation of estradiol combined with testosterone in murine testosterone-deficient NAFLD model.
Authors: Okamura, Takuro and Hamaguchi, Masahide and Bamba, Ryo and Nakajima, Hanako and Yoshimura, Yuta and Kimura, Tomonori and Nishida, Kensuke and Hashimoto, Yoshitaka and Fukuda, Takuya and Senmaru, Takafumi and Fukui, Michiaki
Journal: American journal of physiology. Gastrointestinal and liver physiology (2020)