Name: FITC–dextran conjugate (average MW = ~150K)
Brand: AAT Bioquest
SKU: 21704
Price: 165 USD
Availability: InStock

FITC–dextran conjugate (average MW = ~150K)

FITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. It is also used in microcirculation and cell permeability research utilizing microfluorimetry, and possible in perfusion studies in animals. FITC-dextran has also been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran. Fluorescein-dextran of150 kDa may be used to help assess the integrity of the blood brain barrier (BBB) and to perform fluorescence microlymphography. It may also be used as a microcirculation vascular flux tracer.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
21704	25 mg	Price

Citations

View all 44 citations: Citation Explorer

Vitexin Suppresses High-Glucose-upregulated Adhesion Molecule Expression in Endothelial Cells through Inhibiting NF-$\kappa$B Signaling Pathway

Authors:

Chen, Pie-Che and Chang, Yun-Ching and Tsai, Kun-Ling and Shen, Cheng Huang and Lee, Shin-Da

Journal:

ACS Omega (2024)

Lymphatic Reconnection and Restoration of Lymphatic Flow by Nonvascularized Lymph Node Transplantation: Real-Time Fluorescence Imaging Using Indocyanine Green and Fluorescein Isothiocyanate-Dextran

Authors:

Maeda, T., Yamamoto, Y., Iwasaki, D., Hayashi, T., Funayama, E., Oyama, A., Murao, N., Furukawa, H.

Journal:

Lymphat Res Biol (2018): 165-173

Optimizing Fluorescein Isothiocyanate Dextran Measurement As a Biomarker in a 24-h Feed Restriction Model to Induce Gut Permeability in Broiler Chickens

Authors:

Baxter, M. F. A., Merino-Guzman, R., Latorre, J. D., Mahaffey, B. D., Yang, Y., Teague, K. D., Graham, L. E., Wolfenden, A. D., Hern and ez-Velasco, X., Bielke, L. R., Hargis, B. M., Tellez, G.

Journal:

Front Vet Sci (2017): 56

Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability

Authors:

Natarajan, R., Northrop, N., Yamamoto, B.

Journal:

Curr Protoc Neurosci (2017): 9 58 1-9 58 15

Adenosine receptor agonist NECA increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation

Authors:

Cheng, C. C., Yang, Y. L., Liao, K. H., Lai, T. W.

Journal:

Sci Rep (2016): 23882

Physical properties

Molecular weight	~150000
Solvent	Water
Dye loading	4 - 5

Spectral properties

Correction factor (280 nm)	0.35
Extinction coefficient (cm ^-1 M ^-1)	73000
Excitation (nm)	491
Emission (nm)	516
Quantum yield	0.92

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on September 26, 2025