Name: FITC–dextran conjugate (average MW = ~20K)
Brand: AAT Bioquest
SKU: 21700
Price: 174 USD
Availability: InStock

FITC–dextran conjugate (average MW = ~20K)

FITC-labeled dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. It is also used in microcirculation and cell permeability research utilizing microfluorimetry, and possible in perfusion studies in animals. FITC-dextran has also been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran. Small FITC-dextrans are often used to measure processes such as endocytosis and cell junction permeability. Fluorescein-dextran, 20kDa, may be used to study cell processes (such as endocytosis and osmoporation), endothelial or epithelial monolayer porosity, apical-basolateral movements within cell layers and cell junction permeability and drug release from structures such as hydrogens and collagen minirods.

Catalog	Size	Price	Quantity
21700	25 mg	Price

Citations

View all 44 citations: Citation Explorer

Vitexin Suppresses High-Glucose-upregulated Adhesion Molecule Expression in Endothelial Cells through Inhibiting NF-$\kappa$B Signaling Pathway

Authors:

Chen, Pie-Che and Chang, Yun-Ching and Tsai, Kun-Ling and Shen, Cheng Huang and Lee, Shin-Da

Journal:

ACS Omega (2024)

Lymphatic Reconnection and Restoration of Lymphatic Flow by Nonvascularized Lymph Node Transplantation: Real-Time Fluorescence Imaging Using Indocyanine Green and Fluorescein Isothiocyanate-Dextran

Authors:

Maeda, T., Yamamoto, Y., Iwasaki, D., Hayashi, T., Funayama, E., Oyama, A., Murao, N., Furukawa, H.

Journal:

Lymphat Res Biol (2018): 165-173

Optimizing Fluorescein Isothiocyanate Dextran Measurement As a Biomarker in a 24-h Feed Restriction Model to Induce Gut Permeability in Broiler Chickens

Authors:

Baxter, M. F. A., Merino-Guzman, R., Latorre, J. D., Mahaffey, B. D., Yang, Y., Teague, K. D., Graham, L. E., Wolfenden, A. D., Hern and ez-Velasco, X., Bielke, L. R., Hargis, B. M., Tellez, G.

Journal:

Front Vet Sci (2017): 56

Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability

Authors:

Natarajan, R., Northrop, N., Yamamoto, B.

Journal:

Curr Protoc Neurosci (2017): 9 58 1-9 58 15

Adenosine receptor agonist NECA increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation

Authors:

Cheng, C. C., Yang, Y. L., Liao, K. H., Lai, T. W.

Journal:

Sci Rep (2016): 23882

Physical properties

Molecular weight	~20K
Solvent	Water

Spectral properties

Correction factor (280 nm)	0.35
Extinction coefficient (cm ^-1 M ^-1)	73000
Excitation (nm)	491
Emission (nm)	516
Quantum yield	0.92

Storage, safety and handling

Certificate of Origin	Download PDF
H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on October 17, 2025