Fluorescein-5-maleimide *CAS 75350-46-8*

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Chemical structure for Fluorescein-5-maleimide *CAS 75350-46-8*
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Unit Size: Cat No: Price (USD): Qty:
25 mg 130 $125


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Overview

Ex/Em (nm)491/514
MW427.36
CAS #75350-46-8
SolventDMSO
Storage Freeze (<-15 °C)
Minimize light exposure
Category Peptide Synthesis
Peptide Labeling Reagents
Related Fluoresceins
Thiol-Reactive Probes
Secondary Reagents
Maleimides are among the most frequently used reagents for thiol modification. In most proteins, the site of reaction is at cysteine residues that either are intrinsically present or resulted from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidine and methionine under physiological conditions. Fluorescein-5-maleimide is one of the most popular fluorescent dyes for thiol modifications of proteins along with 5-TMRIA.




Calculators
Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Fluorescein-5-maleimide *CAS 75350-46-8* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.



Molarity calculator

Table 2. Enter any two values (mass, volume, concentration) to calculate the third.

Mass Molecular weight Volume Concentration Moles
/ = x =
 






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References & Citations

Multifunctional superparamagnetic nanoparticles conjugated with fluorescein-labeled designed ankyrin repeat protein as an efficient HER2-targeted probe in breast cancer
Authors: Dong-Li Li, Jian-Er Tan, Ying Tian, Shun Huang, Peng-Hui Sun, Meng Wang, Yan-Jiang Han, Hong-Sheng Li, Hu-Bing Wu, Xing-Mei Zhang
Journal: Biomaterials (2017)

Targeted Mesoporous Silica Nanoparticles Delivering Arsenic Trioxide with Environment Sensitive Drug Release for Effective Treatment of Triple Negative Breast Cancer
Authors: Xiaohui Wu, Zheng Han, Rebecca M Schur, Zheng-Rong Lu
Journal: ACS Biomaterials Science & Engineering (2016): 501--507






Additional Documents

 
Safety Data Sheet (SDS)


Catalogs
1. Oligonucleotide Labeling Reagents
2. Peptide Labeling Reagents

Certificate of Analysis