Name: Goat anti human IgG (Fc) serum
Brand: AAT Bioquest
SKU: 50301
Availability: InStock

Goat anti human IgG (Fc) serum

Anti-Human IgG (Fc specific) antiserum is produced in goat using purified human IgG, Fc fragment, as the immunogen. The antibody preparation is specific for human IgG, Fc fragment when tested against purified human IgA, IgG (Fc and Fab fragments). No reactivity is observed with the Fab fragment of human IgG, light chains, IgA, or IgM. The lack of interspecies cross reactivity with mouse or rat serum proteins makes this product excellent for the screening of human monoclonal antibodies produced by hybridoma cells grown in vivo in mouse or rat ascites fluids. This product has the ability to detect all human IgG subclasses in human biological fluids or tissues of normal or pathological situations such as cancer or autoimmune diseases. It is effective as a second antibody reagent in immunoassay procedures and can be used as starting material for conjugates using enzymes or fluorescent dyes. Anti-Human IgG (Fc specific) antibody produced in goat has been used in double-capture ELISA to measure antiglobulin responses in serum of transplant patients treated with CD52 monoclonal antibodies (CAMPATH-1G), detection of IgG levels rheumatoid arthritis patients, small intestine biopsies and patients with acute myocardial infarction by immunoblotting.

General packaging for Catalog 50301 (1 mL) and 50302 (10 mL). Your actual packaging may vary.

Protocol

COA

Catalog	Size	Price	Quantity
50301	1 mL	Price
50302	10 mL	Price

References

View all 50 references: Citation Explorer

Monoclonal secondary reagents do not outperform polyclonal secondary reagents for detection of anti-HLA IgG using single antigen flow beads assays.

Authors:

Bonnet, Marie and Visentin, Jonathan and Caillat-Zucman, Sophie and Jollet, Isabelle and Taupin, And Jean-Luc

Journal:

HLA (2020)

Immunoglobulin G-Encapsulated Gold Nanoclusters as Fluorescent Tags for Dot-Blot Immunoassays.

Authors:

Zhuang, Quan-Quan and Deng, Hao-Hua and He, Shao-Bin and Peng, Hua-Ping and Lin, Zhen and Xia, Xing-Hua and Chen, Wei

Journal:

ACS applied materials & interfaces (2019): 31729-31734

An infrared IgG immunoassay based on the use of a nanocomposite consisting of silica coated Fe3O4 superparticles.

Authors:

Wang, Kexin and Ding, Yadan and Hong, Xia and Liu, Yichun

Journal:

Mikrochimica acta (2019): 99

A rapid point-of-care test for dengue virus-1 based on a lateral flow assay with a near-infrared fluorescent dye.

Authors:

Chen, Lin and Wang, Huagui and Guo, Tongsheng and Xiao, Chaohui and Liu, Licheng and Zhang, Xiaoguang and Liu, Bo and Li, Peiran and Liu, Aixia and Li, Bo and Li, Boan and Mao, Yuanli

Journal:

Journal of immunological methods (2018): 23-27

Assembly of Multifunctionalized Gold Nanoparticles with Chemiluminescent, Catalytic, and Immune Activity for Label-Free Immunoassays.

Authors:

Huang, Yao and Gao, Lingfeng and Cui, Hua

Journal:

ACS applied materials & interfaces (2018): 17040-17046

Physical properties

Solvent

N/A

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Refrigerated (2-8 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on October 9, 2025