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Helixyte™ Green Amine
Helixyte™ Green is an excellent nucleic acid sensor that exhibits large fluorescence enhancement upon binding to dsDNA. It has the same spectral and DNA-binding properties as SYBR Green® (SYBR Green® is the trademark of ThermoFisher). AAT Bioquest’s scientists developed Helixyte™ Green amine to enable the development of site-specific DNA probes. Helixyte™ Green amine is an excellent building block that readily reacts with carbonyl-containing biological molecules such as peptides, antibodies and other proteins. Thus, it can be used to develop a variety of site-directed DNA probes. Helixyte™ Green is an excellent fluorogenic probe for quantifying DNAs with greatly improved sensitivity and selectivity. Helixyte™ Green is an ultra-sensitive fluorescent nucleic acid stain for quantitating double-stranded DNA (dsDNA) in molecular biological procedures such as cDNA synthesis for library production and DNA fragment purification for subcloning, as well as diagnostic applications, such as quantitating DNA amplification products and primer extension assays.
Spectrum
References
View all 50 references: Citation Explorer
Rational Design of Hydroxylated Thiazole Orange Photocages for Green Light-Triggered DNA Recombination.
Authors: Hashimoto, Ryu and Minoshima, Masafumi and Kikuchi, Kazuya
Journal: Chembiochem : a European journal of chemical biology (2024): e202300799
Authors: Hashimoto, Ryu and Minoshima, Masafumi and Kikuchi, Kazuya
Journal: Chembiochem : a European journal of chemical biology (2024): e202300799
Thiazole orange-carboplatin triplex-forming oligonucleotide (TFO) combination probes enhance targeted DNA crosslinking.
Authors: Hennessy, Joseph and Klimkowski, Piotr and Singleton, Daniel and Gibney, Alex and Coche, Malou and Farrell, Nicholas P and El-Sagheer, Afaf H and Brown, Tom and Kellett, Andrew
Journal: RSC medicinal chemistry (2024): 485-491
Authors: Hennessy, Joseph and Klimkowski, Piotr and Singleton, Daniel and Gibney, Alex and Coche, Malou and Farrell, Nicholas P and El-Sagheer, Afaf H and Brown, Tom and Kellett, Andrew
Journal: RSC medicinal chemistry (2024): 485-491
In vitro Selection and Characterization of a Light-up DNA Aptamer for Thiazole Orange.
Authors: La, Volition and Evans, Natasha M and Hong, Aiden and Tormann, Alexandra and Shivers, Lindsey and Dieckmann, Thorsten
Journal: Chembiochem : a European journal of chemical biology (2024): e202400444
Authors: La, Volition and Evans, Natasha M and Hong, Aiden and Tormann, Alexandra and Shivers, Lindsey and Dieckmann, Thorsten
Journal: Chembiochem : a European journal of chemical biology (2024): e202400444
RNA G-quadruplex in live cells lighted-up by a thiazole orange analogue for SCA36 identification.
Authors: Sun, Ranran and Guo, Xiaomeng and Yang, Dawei and Cai, Xinchen and Li, Qian and Yao, Li and Sun, Hongxia and Tang, Yalin
Journal: International journal of biological macromolecules (2023): 724-731
Authors: Sun, Ranran and Guo, Xiaomeng and Yang, Dawei and Cai, Xinchen and Li, Qian and Yao, Li and Sun, Hongxia and Tang, Yalin
Journal: International journal of biological macromolecules (2023): 724-731
Classical thiazole orange and its regioisomer as fluorogenic probes for nucleolar RNA imaging in living cells.
Authors: He, Mengmeng and Sato, Yusuke and Nishizawa, Seiichi
Journal: The Analyst (2023): 636-642
Authors: He, Mengmeng and Sato, Yusuke and Nishizawa, Seiichi
Journal: The Analyst (2023): 636-642
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