ICG amine | AAT Bioquest

ICG amine

Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption close to 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. This ICG amine can be used to modify the molecules that contain a carbonyl group (such as an aldehyde or a carboxy group).

Protocol

COA

Catalog	Size	Price	Quantity
188	1 mg	Price
188-5MG	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of ICG amine to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	99.892 µL	499.461 µL	998.921 µL	4.995 mL	9.989 mL
5 mM	19.978 µL	99.892 µL	199.784 µL	998.921 µL	1.998 mL
10 mM	9.989 µL	49.946 µL	99.892 µL	499.461 µL	998.921 µL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	1001.08 g/mol	=	mL	x	mM	=	mmol

Citations

View all 8 citations: Citation Explorer

Real-Time in Vivo Bacterial Imaging by Computed Tomography and Fluorescence Using Phage-Gold Nanorod Bioconjugates as Contrast Agents

Authors:

Peng, Huan and Vexler, Shelby and Xu, Shili and Chen, Irene A

Journal:

ACS Biomaterials Science \& Engineering (2025)

Comparison of Near-Infrared Imaging Agents Targeting the PTPmu Tumor Biomarker

Authors:

Johansen, Mette L and Vincent, Jason and Rose, Marissa and Sloan, Andrew E and Brady-Kalnay, Susann M

Journal:

Molecular Imaging and Biology (2023): 1--14

Intravenous anti-VEGF agents with RGD peptide-targeted core cross-linked star (CCS) polymers modified with indocyanine green for imaging and treatment of laser-induced choroidal neovascularization

Authors:

Cai, Wenting and Chen, Qijing and Shen, Tianyi and Yang, Qian and Hu, Weinan and Zhao, Peng and Yu, Jing

Journal:

Biomaterials Science (2020): 4481--4491

Assessment of Lexiscan for Blood Brain Barrier disruption to facilitate Fluorescence brain imaging

Authors:

Pak, Rebecca W and Le, Hanh ND and Valentine, Heather and Thorek, Daniel and Rahmim, Arman and Wong, Dean and Kang, Jin U

Assessment of Lexiscan for Blood Brain Barrier disruption to facilitate Fluorescence brain imaging

Authors:

Pak, Rebecca W and Le, Hanh and Valentine, Heather and Thorek, Daniel and Rahmim, Arman and Wong, Dean and Kang, Jin U

References

View all 193 references: Citation Explorer

Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer

Authors:

Yuasa Y, Seike J, Yoshida T, Takechi H, Yamai H, Yamamoto Y, Furukita Y, Goto M, Minato T, Nishino T, Inoue S, Fujiwara S, Tangoku A.

Journal:

Ann Surg Oncol (2012): 486

Indocyanine green angiography-guided photodynamic therapy for treatment of chronic central serous chorioretinopathy: a pilot study

Authors:

Yannuzzi LA, Slakter JS, Gross NE, Spaide RF, Costa DL, Huang SJ, Klancnik JM, Jr., Aizman A.

Journal:

Retina (2012): 288

Using indocyanine green fluorescent lymphography and lymphatic-venous anastomosis for cancer-related lymphedema

Authors:

Mihara M, Murai N, Hayashi Y, Hara H, Iida T, Narushima M, Todokoro T, Uchida G, Yamamoto T, Koshima I.

Journal:

Ann Vasc Surg (2012): 278 e1

Indocyanine green fluorescence endoscopy for visual differentiation of pituitary tumor from surrounding structures

Authors:

Litvack ZN, Zada G, Laws ER, Jr.

Journal:

J Neurosurg. (2012)

Management of peripheral polypoidal choroidal vasculopathy with intravitreal bevacizumab and indocyanine green angiography-guided laser photocoagulation

Authors:

Rishi P, Das A, Sarate P, Rishi E.

Journal:

Indian J Ophthalmol (2012): 60

Physical properties

Molecular weight	1001.08
Solvent	DMSO

Spectral properties

Correction factor (280 nm)	0.076
Extinction coefficient (cm ^-1 M ^-1)	230000
Excitation (nm)	789
Emission (nm)	813

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

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Page updated on October 8, 2025