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IP1 Amine

Product key features

  • An excellent building block to develop IP1 probes 
  • Readily reacts with carbonyl compounds
  • Might be used for detecting myo-inositol

Product description

IP1 Amine is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1). It readily reacts with carbonyl-containing biomolecules (such as peptides and antibodies). IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.

References

View all 4 references: Citation Explorer
Phosphonate and α-Fluorophosphonate Analogues of d-Glucose 6-Phosphate as Active-Site Probes of 1l-myo-Inositol 1-Phosphate Synthase.
Authors: Ramos-Figueroa, Josseline S and Palmer, David R J
Journal: Biochemistry (2022): 868-878
Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation.
Authors: Waring, Michael J and Andrews, David M and Faulder, Paul F and Flemington, Vikki and McKelvie, Jennifer C and Maman, Sarita and Preston, Marian and Raubo, Piotr and Robb, Graeme R and Roberts, Karen and Rowlinson, Rachel and Smith, James M and Swarbrick, Martin E and Treinies, Iris and Winter, Jon J G and Wood, Robert J
Journal: Chemical communications (Cambridge, England) (2014): 5388-90
Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase.
Authors: Neelon, Kelly and Wang, Yan and Stec, Boguslaw and Roberts, Mary F
Journal: The Journal of biological chemistry (2005): 11475-82
Metabotropic glutamate receptors in cultured cerebellar granule cells: developmental profile.
Authors: Aronica, E and Condorelli, D F and Nicoletti, F and Dell'Albani, P and Amico, C and Balázs, R
Journal: Journal of neurochemistry (1993): 559-65
Page updated on May 19, 2025

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Catalog Number20344
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Physical properties

Molecular weight

303.20

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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