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IP1 Azide
Product key features
- An excellent building block to develop IP1 probes
- Readily reacts with alkynyl compounds
- Might be used for detecting myo-inositol
Product description
IP1 Azide is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1) via the well known click chemistry (CuAAC). It readily reacts with alkynyl-containing biomolecules (such as peptides, antibodies and alkynyl-modified oligos) under extremely mild conditions. IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.
References
View all 49 references: Citation Explorer
SCA44- and SCAR13-associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms.
Authors: Wang, Yuyang and Muraleetharan, Ashwin and Langiu, Monica and Gregory, Karen J and Hellyer, Shane D
Journal: British journal of pharmacology (2024)
Authors: Wang, Yuyang and Muraleetharan, Ashwin and Langiu, Monica and Gregory, Karen J and Hellyer, Shane D
Journal: British journal of pharmacology (2024)
Direct Stimulatory Effects of the CB2 Ligand JTE 907 in Human and Mouse Islets.
Authors: Ruz-Maldonado, Inmaculada and Atanes, Patricio and Huang, Guo Cai and Liu, Bo and Persaud, Shanta J
Journal: Cells (2021)
Authors: Ruz-Maldonado, Inmaculada and Atanes, Patricio and Huang, Guo Cai and Liu, Bo and Persaud, Shanta J
Journal: Cells (2021)
Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors.
Authors: Maspero, Marco and Volpato, Daniela and Cirillo, Davide and Yuan Chen, Natalia and Messerer, Regina and Sotriffer, Christoph and De Amici, Marco and Holzgrabe, Ulrike and Dallanoce, Clelia
Journal: Bioorganic chemistry (2020): 103633
Authors: Maspero, Marco and Volpato, Daniela and Cirillo, Davide and Yuan Chen, Natalia and Messerer, Regina and Sotriffer, Christoph and De Amici, Marco and Holzgrabe, Ulrike and Dallanoce, Clelia
Journal: Bioorganic chemistry (2020): 103633
Isolation of rat hepatocytes for pharmacological studies on metabotropic glutamate receptor (mGluR) subtype 5: a comparison between collagenase I versus collagenase IV.
Authors: Berardo, Clarissa and Ferrigno, Andrea and Siciliano, Veronica and Richelmi, Plinio and Vairetti, Mariapia and Di Pasqua, Laura Giuseppina
Journal: European journal of histochemistry : EJH (2020)
Authors: Berardo, Clarissa and Ferrigno, Andrea and Siciliano, Veronica and Richelmi, Plinio and Vairetti, Mariapia and Di Pasqua, Laura Giuseppina
Journal: European journal of histochemistry : EJH (2020)
Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors.
Authors: Perdona, Elisabetta and Cavallini, Palmina and Sava, Anna and Griffante, Cristiana and Ricca, Daniel J and Thor, Karl B and Rupniak, Nadia M J and Corsi, Mauro
Journal: Neuroscience letters (2019): 134456
Authors: Perdona, Elisabetta and Cavallini, Palmina and Sava, Anna and Griffante, Cristiana and Ricca, Daniel J and Thor, Karl B and Rupniak, Nadia M J and Corsi, Mauro
Journal: Neuroscience letters (2019): 134456
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