Name: IP1 Azide
Brand: AAT Bioquest
SKU: 20342
Price: 469 USD
Availability: InStock

IP1 Azide

IP1 azide is an azide-functionalized myo-inositol 1-phosphate analog that enables bioorthogonal labeling via click chemistry for creating IP1 detection probes and investigating phosphoinositide metabolism.

Azide Functionality: Reacts with alkynes via CuAAC or strain-promoted click chemistry
Bioorthogonal Labeling: Compatible with DBCO and other alkyne reagents for copper-free reactions
IP1 Assay Development: Builds fluorescent or enzymatic probes for IP1 quantification
Cell Signaling Research: Studies phospholipase C activity and IP3/IP1 metabolism

Datasheet

SDS

COA

Catalog	Size	Price	Quantity
20342	100 ug	Price

Overview

IP1 Azide is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1) via the well known click chemistry (CuAAC). It readily reacts with alkynyl-containing biomolecules (such as peptides, antibodies and alkynyl-modified oligos) under extremely mild conditions. IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of IP1 Azide to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	226.06 µL	1.13 mL	2.261 mL	11.303 mL	22.606 mL
5 mM	45.212 µL	226.06 µL	452.12 µL	2.261 mL	4.521 mL
10 mM	22.606 µL	113.03 µL	226.06 µL	1.13 mL	2.261 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	442.36 g/mol	=	mL	x	mM	=	mmol

References

View all 49 references: Citation Explorer

SCA44- and SCAR13-associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms.

Authors:

Wang, Yuyang and Muraleetharan, Ashwin and Langiu, Monica and Gregory, Karen J and Hellyer, Shane D

Journal:

British journal of pharmacology (2024)

Direct Stimulatory Effects of the CB2 Ligand JTE 907 in Human and Mouse Islets.

Authors:

Ruz-Maldonado, Inmaculada and Atanes, Patricio and Huang, Guo Cai and Liu, Bo and Persaud, Shanta J

Journal:

Cells (2021)

Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors.

Authors:

Maspero, Marco and Volpato, Daniela and Cirillo, Davide and Yuan Chen, Natalia and Messerer, Regina and Sotriffer, Christoph and De Amici, Marco and Holzgrabe, Ulrike and Dallanoce, Clelia

Journal:

Bioorganic chemistry (2020): 103633

Isolation of rat hepatocytes for pharmacological studies on metabotropic glutamate receptor (mGluR) subtype 5: a comparison between collagenase I versus collagenase IV.

Authors:

Berardo, Clarissa and Ferrigno, Andrea and Siciliano, Veronica and Richelmi, Plinio and Vairetti, Mariapia and Di Pasqua, Laura Giuseppina

Journal:

European journal of histochemistry : EJH (2020)

Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors.

Authors:

Perdona, Elisabetta and Cavallini, Palmina and Sava, Anna and Griffante, Cristiana and Ricca, Daniel J and Thor, Karl B and Rupniak, Nadia M J and Corsi, Mauro

Journal:

Neuroscience letters (2019): 134456

Physical properties

Molecular weight	442.36
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

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Page updated on January 8, 2026