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IP1 Maleimide

Product key features

  • An excellent building block to develop IP1 probes
  • Readily reacts with thiol compounds
  • Might be used for detecting myo-inositol

Product description

IP1 Maleimide is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1). It readily reacts with thiol-containing biomolecules (such as peptides, antibodies and thiol-modified oligos) under extremely mild conditions. IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.

References

View all 50 references: Citation Explorer
A new look at angiogenesis inhibition of geniposide in experimental arthritis by blocking angiopoietin-2 exocytosis.
Authors: Gan, Peirong and Wu, Hong and Zhu, Yulong and Shu, Yin and Wei, Yi
Journal: Phytotherapy research : PTR (2024): 1245-1261
SCA44- and SCAR13-associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms.
Authors: Wang, Yuyang and Muraleetharan, Ashwin and Langiu, Monica and Gregory, Karen J and Hellyer, Shane D
Journal: British journal of pharmacology (2024)
Non-inositol 1,4,5-trisphosphate (IP3) receptor IP3-binding proteins.
Authors: Mackrill, John James
Journal: Biochimica et biophysica acta. Molecular cell research (2023): 119470
The pair ceramide 1-phosphate/ceramide kinase regulates intracellular calcium and progesterone-induced human sperm acrosomal exocytosis.
Authors: Vaquer, Cintia C and Suhaiman, Laila and Pavarotti, Martín A and Arias, Rodolfo J and Pacheco Guiñazú, Anahí B and De Blas, Gerardo A and Belmonte, Silvia A
Journal: Frontiers in cell and developmental biology (2023): 1148831
A mutation in Arabidopsis SAL1 alters its in vitro activity against IP3 and delays developmental leaf senescence in association with lower ROS levels.
Authors: Shirzadian-Khorramabad, Reza and Moazzenzadeh, Taghi and Sajedi, Reza H and Jing, Hai-Chun and Hille, Jacques and Dijkwel, Paul P
Journal: Plant molecular biology (2022): 549-563
Page updated on May 19, 2025

Ordering information

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Catalog Number20341
Quantity
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Physical properties

Molecular weight

454.32

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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