Name: IP1 Succinimidyl Ester
Brand: AAT Bioquest
SKU: 20340
Price: 781 USD
Availability: InStock

IP1 Succinimidyl Ester

IP1 succinimidyl ester is an amine-reactive myo-inositol 1-phosphate derivative that forms stable amide bonds with lysine residues, enabling creation of IP1-specific antibodies and detection reagents.

NHS ester Chemistry: Efficiently labels primary amines at pH 7–9 forming stable amide bonds
Protein Conjugation: Modifies lysine residues and N-terminal amines on antibodies and enzymes
IP1 Hapten Synthesis: Creates immunogenic conjugates for monoclonal antibody production
HTRF Assay Development: Builds labeled IP1 derivatives for homogeneous TR-FRET assays

Datasheet

SDS

COA

Catalog	Size	Price	Quantity
20340	100 ug	Price

Overview

IP1 Succinimidyl Ester is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1). It readily reacts with amino group-containing biomolecules (such as peptides, antibodies and amino-modified oligos) under extremely mild conditions. IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to a myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of IP1 Succinimidyl Ester to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	212.157 µL	1.061 mL	2.122 mL	10.608 mL	21.216 mL
5 mM	42.431 µL	212.157 µL	424.313 µL	2.122 mL	4.243 mL
10 mM	21.216 µL	106.078 µL	212.157 µL	1.061 mL	2.122 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	471.35 g/mol	=	mL	x	mM	=	mmol

References

View all 50 references: Citation Explorer

Phosphonate and α-fluorophosphonate analogs of d-glucose 6-phosphate as active-site probes of 1l-myo-inositol 1-phosphate synthase.

Authors:

Ramos-Figueroa, Josseline S and Vetter, Natasha D and Palmer, David R J

Journal:

Methods in enzymology (2023): 57-93

Phosphonate and α-Fluorophosphonate Analogues of d-Glucose 6-Phosphate as Active-Site Probes of 1l-myo-Inositol 1-Phosphate Synthase.

Authors:

Ramos-Figueroa, Josseline S and Palmer, David R J

Journal:

Biochemistry (2022): 868-878

In-silico studies on Myo inositol-1-phosphate synthase of Leishmania donovani in search of anti-leishmaniasis.

Authors:

Sinha, Mousumi and Jagadeesan, Rahul and Kumar, Neeraj and Saha, Satabdi and Kothandan, Gugan and Kumar, Diwakar

Journal:

Journal of biomolecular structure & dynamics (2022): 3371-3384

Generation and Characterization of a Soybean Line with a Vernonia galamensis Diacylglycerol Acyltransferase-1 Gene and a myo-Inositol 1-Phosphate Synthase Knockout Mutation.

Authors:

Al-Amery, Maythem and Fowler, Ashley and Unrine, Jason M and Armstrong, Paul and Maghirang, Elizabeth and Su, Kai and de Melo, Julia and Yuan, Feng-Jie and Shu, Qing-Yao and Hildebrand, David

Journal:

Lipids (2020): 469-477

Myo-inositol-1-phosphate synthase (Ino-1) functions as a protection mechanism in Corynebacterium glutamicum under oxidative stress.

Authors:

Chen, Can and Chen, Keqi and Su, Tao and Zhang, Bing and Li, Guizhi and Pan, Junfeng and Si, Meiru

Journal:

MicrobiologyOpen (2019): e00721

Physical properties

Molecular weight	471.35
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

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Page updated on February 28, 2026