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IP1 Succinimidyl Ester

Product key features

  • An excellent building block to develop IP1 probes
  • Readily reacts with amino compounds
  • Might be used for detecting myo-inositol

Product description

IP1 Succinimidyl Ester is an excellent building block to develop probes for detecting 1D-myo-inositol 1-phosphate (IP1). It readily reacts with amino group-containing biomolecules (such as peptides, antibodies and amino-modified oligos) under extremely mild conditions. IP1 is an inositol having myo- configuration substituted at position 1 by a phosphate group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. IP1 is functionally related to a myo-inositol. It is a conjugate acid of 1D-myo-inositol 1-phosphate.

References

View all 50 references: Citation Explorer
Phosphonate and α-fluorophosphonate analogs of d-glucose 6-phosphate as active-site probes of 1l-myo-inositol 1-phosphate synthase.
Authors: Ramos-Figueroa, Josseline S and Vetter, Natasha D and Palmer, David R J
Journal: Methods in enzymology (2023): 57-93
Phosphonate and α-Fluorophosphonate Analogues of d-Glucose 6-Phosphate as Active-Site Probes of 1l-myo-Inositol 1-Phosphate Synthase.
Authors: Ramos-Figueroa, Josseline S and Palmer, David R J
Journal: Biochemistry (2022): 868-878
In-silico studies on Myo inositol-1-phosphate synthase of Leishmania donovani in search of anti-leishmaniasis.
Authors: Sinha, Mousumi and Jagadeesan, Rahul and Kumar, Neeraj and Saha, Satabdi and Kothandan, Gugan and Kumar, Diwakar
Journal: Journal of biomolecular structure & dynamics (2022): 3371-3384
Generation and Characterization of a Soybean Line with a Vernonia galamensis Diacylglycerol Acyltransferase-1 Gene and a myo-Inositol 1-Phosphate Synthase Knockout Mutation.
Authors: Al-Amery, Maythem and Fowler, Ashley and Unrine, Jason M and Armstrong, Paul and Maghirang, Elizabeth and Su, Kai and de Melo, Julia and Yuan, Feng-Jie and Shu, Qing-Yao and Hildebrand, David
Journal: Lipids (2020): 469-477
Myo-inositol-1-phosphate synthase (Ino-1) functions as a protection mechanism in Corynebacterium glutamicum under oxidative stress.
Authors: Chen, Can and Chen, Keqi and Su, Tao and Zhang, Bing and Li, Guizhi and Pan, Junfeng and Si, Meiru
Journal: MicrobiologyOpen (2019): e00721
Page updated on April 25, 2025

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Catalog Number20340
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Physical properties

Molecular weight

471.35

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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