Name: Leu-AMC [L-Leucine-7-amido-4-methylcoumarin] *CAS 62480-44-8*
Brand: AAT Bioquest
SKU: 13445
Price: 174 USD
Availability: InStock

Leu-AMC

L-Leucine-7-amido-4-methylcoumarin; CAS 62480-44-8

Leu-AMC is a fluorogenic substrate for leucine aminopeptidase. Upon the hydrolysis by proteases, Leu-AMC releases the strongly fluorescent AMC fluorophore.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
13445	10 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Leu-AMC [L-Leucine-7-amido-4-methylcoumarin] *CAS 62480-44-8* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	307.882 µL	1.539 mL	3.079 mL	15.394 mL	30.788 mL
5 mM	61.576 µL	307.882 µL	615.764 µL	3.079 mL	6.158 mL
10 mM	30.788 µL	153.941 µL	307.882 µL	1.539 mL	3.079 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	324.8 g/mol	=	mL	x	mM	=	mmol

References

View all 39 references: Citation Explorer

Molecular and biochemical characterization of methionine aminopeptidase of Babesia bovis as a potent drug target

Authors:

Munkhjargal T, Ishizaki T, Guswanto A, Takemae H, Yokoyama N, Igarashi I.

Journal:

Vet Parasitol (2016): 14

Secretory Expression, Purification, Characterization, and Application of an Aspergillus oryzae Prolyl Aminopeptidase in Bacillus subtilis

Authors:

Wang KD, Wang KH, Zhou ND, Tian YP.

Journal:

Appl Biochem Biotechnol. (2016)

Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9

Authors:

Wang X, Shi L, Deng Y, Qu M, Mao S, Xu L, Xu W, Fang C.

Journal:

Eur J Pharmacol (2015): 116

Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii

Authors:

Lee YR, Na BK, Moon EK, Song SM, Joo SY, Kong HH, Goo YK, Chung DI, Hong Y.

Journal:

PLoS One (2015): e0129884

Molecular Characterization of Babesia bovis M17 Leucine Aminopeptidase and Inhibition of Babesia Growth by Bestatin

Authors:

Aboge GO, Cao S, Terkawi MA, Masatani T, Goo Y, AbouLaila M, Nishikawa Y, Igarashi I, Suzuki H, Xuan X.

Journal:

J Parasitol (2015): 536

Physical properties

Molecular weight	324.80
Solvent	DMSO

Spectral properties

Excitation (nm)	341
Emission (nm)	441

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	62480-44-8

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Page updated on October 15, 2025