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Lissamine Rhodamine B Sulfonyl Chloride
Sulforhodamine B sulfonyl chloride; CAS 62796-29-6
SRB sulfonyl chloride (also called Lissamine rhodamine sulfonyl chloride™) is highly fluorescent. It is quite unstable in water, especially at the higher pH required for reaction with aliphatic amines. Protein modification by this reagent is frequently done at low temperature (preferably at 4 °C). This reagent reacts with amine compounds such as amino acids, peptides and proteins to give bright red fluorescent conjugates that are extremely stable, and resistant to protease-catalyzed hydrolysis. Unlike succinimidyl esters, sulfonyl chlorides react with both aliphatic amines and aromatic amines indiscriminatingly.
Chemical structure for Lissamine Rhodamine B Sulfonyl Chloride [Sulforhodamine B sulfonyl chloride] *CAS 62796-29-6*
Chemical structure for Lissamine Rhodamine B Sulfonyl Chloride [Sulforhodamine B sulfonyl chloride] *CAS 62796-29-6*
CatalogSize
Price
Quantity
470100 mg
Price
 
Physical properties

Molecular weight577.11
SolventDMF
Spectral properties

Correction factor (260 nm)0.21
Correction factor (280 nm)0.171
Excitation (nm)558
Emission (nm)575
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
CAS62796-29-6
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Page updated on October 13, 2025