mFluor™ Violet 540 Anti-human CD267 Antibody *1A1*

The 1A1 monoclonal antibody binds with human CD267, a 32 kD single-pass type iii membrane protein typically found on the surface of meyloma cells and B cells. CD267 is a component of important cellular pathways, namely, the tumor necrosis factor-mediated signaling pathway and cell surface receptor signaling pathway. Also, in some organisms, it is a suppressor of B cell proliferation. From a research standpoint, it is of biological interest due to its association with important macromolecules/ligands like BAFF, BLYS and TALL1. CD267 is a relatively rare antibody target, with fewer than 50 publications in the last decade. Even still, CD267 has been widely used in costimulatory molecules and immunology research, frequently serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to mFluor™ Violet 540 (ex/em = 394/537 nm). It is compatible with the 405 nm laser and 530/30 nm bandpass filter (for example, as in the Agilent Technologies NovoCyte).

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