FM 1-43 (MM 1-43) | AAT Bioquest

MM 1-43

N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide; CAS#: 149838-22-2

MM 1-43 is the abbreviation of our Membrane Marker 1-43, chemically called N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide. MM 1-43 is chemically the same molecule of FM 1-43. In literature this membrane marker is also called "FM 1-43" (FM® is the trademark of Molecular Probes). It is a water-soluble membrane probe that belongs to the styryl dye family. It is widely used in cell biology and neurobiology since it has minimal toxicity to cells. MM 1-43 is virtually non-fluorescent in aqueous medium and strongly fluorescent upon binding to membrane. It is efficiently excited with standard fluorescein optical filters, and exhibits an intense fluorescent signal when associated with the plasma membrane. MM 1-43 has frequently been used to quantify exocytosis in neurons. Fluorescence imaging using MM 1-43 and related styryl dyes has provided invaluable insights into presynaptic function of synapses in culture preparations.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
21483	1 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of Water needed to reconstitute specific mass of MM 1-43 [N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide] *CAS#: 149838-22-2* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	163.522 µL	817.608 µL	1.635 mL	8.176 mL	16.352 mL
5 mM	32.704 µL	163.522 µL	327.043 µL	1.635 mL	3.27 mL
10 mM	16.352 µL	81.761 µL	163.522 µL	817.608 µL	1.635 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	611.54 g/mol	=	mL	x	mM	=	mmol

References

View all 27 references: Citation Explorer

Palytoxin-induced effects on partial reactions of the Na,K-ATPase

Authors:

Harmel N, Apell HJ.

Journal:

J Gen Physiol (2006): 103

Electrogenic partial reactions of the gastric H,K-ATPase

Authors:

Diller A, Vagin O, Sachs G, Apell HJ.

Journal:

Biophys J (2005): 3348

Effective gating charge of ion channels induced by toxin syringomycin E in lipid bilayers

Authors:

Schagina LV, Gurnev PA, Takemoto JY, Malev VV.

Journal:

Bioelectrochemistry (2003): 21

Effect of dipole modifiers on the kinetics of sensitized photoinactivation of gramicidin channels in bilayer lipid membranes

Authors:

Antonenko YN, Rokitskaya TI, Kotova EA.

Journal:

Membr Cell Biol (1999): 111

Hofmeister effects of anions on the kinetics of partial reactions of the Na+,K+-ATPase

Authors:

Ganea C, Babes A, Lupfert C, Grell E, Fendler K, Clarke RJ.

Journal:

Biophys J (1999): 267

Physical properties

Molecular weight	611.54
Solvent	Water

Spectral properties

Excitation (nm)	473
Emission (nm)	579

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	149838-22-2

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Page updated on January 22, 2025