Name: MM 4-64 Fixable Membrane Stain
Brand: AAT Bioquest
SKU: 21488
Price: 250 USD
Availability: InStock

MM 4-64 Fixable Membrane Stain

MM4-64 Fixable Membrane Stain is a lipophilic red-fluorescent probe that selectively labels plasma membranes and remains fixed in place after aldehyde treatment, ideal for studying membrane dynamics and endocytosis.

Selective Membrane Labeling: Strong, localized fluorescence upon plasma membrane binding
Rapid, Reversible Binding: Ideal for real-time dynamic imaging studies
Fixation-Compatible: Compatible with aldehyde fixation for staining preservation
Neuroscientific Application: Ideal for active neuron detection and vesicle cycling studies

Protocol

SDS

COA

Catalog	Size	Price	Quantity
21488	5x100 ug	Price

Overview

MM4-64 Fixable Membrane Stain is a lipophilic probe optimized for selective plasma membrane labeling. In aqueous solution, it exhibits minimal fluorescence; however, upon binding to the outer leaflet of the plasma membrane, it produces robust fluorescence, enabling precise and reliable membrane visualization. The binding kinetics are both rapid and reversible, supporting its use in aldehyde-based fixation protocols without compromising staining integrity. Furthermore, MM4-64 Fixable Membrane Stain is particularly valuable in neuroscientific applications for identifying active neurons and examining mechanisms involved in activity-dependent vesicle cycling.

Calculators

Common stock solution preparation

Table 1. Volume of Water needed to reconstitute specific mass of MM 4-64 Fixable Membrane Stain to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	126.783 µL	633.914 µL	1.268 mL	6.339 mL	12.678 mL
5 mM	25.357 µL	126.783 µL	253.566 µL	1.268 mL	2.536 mL
10 mM	12.678 µL	63.391 µL	126.783 µL	633.914 µL	1.268 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	788.75 g/mol	=	mL	x	mM	=	mmol

References

View all 50 references: Citation Explorer

Automated quantification of vacuole fusion and lipophagy in Saccharomyces cerevisiae from fluorescence and cryo-soft X-ray microscopy data using deep learning.

Authors:

Egebjerg, Jacob Marcus and Szomek, Maria and Thaysen, Katja and Juhl, Alice Dupont and Kozakijevic, Suzana and Werner, Stephan and Pratsch, Christoph and Schneider, Gerd and Kapishnikov, Sergey and Ekman, Axel and Röttger, Richard and Wüstner, Daniel

Journal:

Autophagy (2024): 902-922

Comparison of Methods for Quantifying Extracellular Vesicles of Gram-Negative Bacteria.

Authors:

Mosby, Chanel A and Perez Devia, Natalia and Jones, Melissa K

Journal:

International journal of molecular sciences (2023)

Concentration-Dependent Antibacterial Activity of Chitosan on Lactobacillus plantarum.

Authors:

Kovács, Renátó and Erdélyi, Lóránd and Fenyvesi, Ferenc and Balla, Noémi and Kovács, Fruzsina and Vámosi, György and Klusóczki, Ágnes and Gyöngyösi, Alexandra and Bácskay, Ildikó and Vecsernyés, Miklós and Váradi, Judit

Journal:

Pharmaceutics (2022)

Stomata in Close Contact: The Case of Pancratium maritimum L. (Amaryllidaceae).

Authors:

Saridis, Pavlos and Georgiadou, Xenia and Shtein, Ilana and Pouris, John and Panteris, Emmanuel and Rhizopoulou, Sophia and Constantinidis, Theophanis and Giannoutsou, Eleni and Adamakis, Ioannis-Dimosthenis S

Journal:

Plants (Basel, Switzerland) (2022)

Phosphatidylserine Is Required for the Normal Progression of Cell Plate Formation in Arabidopsis Root Meristems.

Authors:

Yamaoka, Yasuyo and Shin, Seungjun and Lee, Yuree and Ito, Masaki and Lee, Youngsook and Nishida, Ikuo

Journal:

Plant & cell physiology (2021): 1396-1408

Physical properties

Molecular weight	788.75
Solvent	Water

Spectral properties

Excitation (nm)	506
Emission (nm)	725

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on November 20, 2025