Mouse Anti-PEG mAb [Anti-Polyethylene glycol monoclonal antibody]

Mouse Anti-PEG mAb

Anti-Polyethylene glycol monoclonal antibody

PEG Antibody, mAb, Mouse has high affinity for the PEG backbone. The antibody binds to the variety of PEG such as PEG40K, PEG20K, PEG5K, PEG12, PEGylated drugs and PEG conjugates.Some reagents such as Tween-20, Triton X-100 and NP-40 interfere with the PEG antibody interaction due to structural similarity to PEG. Antibody solution should not contain such reagents in the assay of PEGylated molecules.

ELISA analysis of PEG40K-OVA that was coated on microplate wells, and detected with PEG20K-Biotin in combination with streptavidin-HRP conjugate.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
57000	50 ug	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of peg antibody with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

References

View all 50 references: Citation Explorer

Beyond hydrophilic polymers in amphiphilic polymer-based self-assembled NanoCarriers: Small hydrophilic carboxylate-capped disulfide drug delivery system and its multifunctionality and multispatial targetability.

Authors:

Choi, Yeon Su and Cho, Hana and Choi, Won-Gu and Lee, Sung Su and Huh, Kang Moo and Shim, Min Suk and Park, In Suh and Cho, Yong-Yeon and Lee, Joo Young and Lee, Hye Suk and Kang, Han Chang

Journal:

Biomaterials (2022): 121307

A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes.

Authors:

Talkington, Anne M and McSweeney, Morgan D and Wessler, Timothy and Rath, Marielle K and Li, Zibo and Zhang, Tao and Yuan, Hong and Frank, Jonathan E and Forest, M Gregory and Cao, Yanguang and Lai, Samuel K

Journal:

Journal of controlled release : official journal of the Controlled Release Society (2022): 518-527

Subvisible Particles Derived by Dropping Stress Enhance Anti-PEG Antibody Production and Clearance of PEGylated Proteins in Mice.

Authors:

Nakajima, Takaki and Nagano, Kazuya and Fukuda, Yuka and Ishima, Yu and Shibata, Hiroko and Isaka, Ryo and Zhang, Tian-Qi and Haga, Yuya and Higashisaka, Kazuma and Tsujino, Hirofumi and Ishida, Tatsuhiro and Ishii-Watabe, Akiko and Tsutsumi, Yasuo

Journal:

Journal of pharmaceutical sciences (2022): 1363-1369

Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats.

Authors:

Fang, Jia-Long and Vanlandingham, Michelle M and Beland, Frederick A and Felton, Robert P and Maisha, Mackean P and Olson, Greg R and Patton, Ralph E and Rosenberg, Amy S and Gamboa da Costa, Gonçalo

Journal:

Toxicology letters (2022): 22-30

Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation.

Authors:

Mostafa, Mahmoud and Elsadek, Nehal E and Emam, Sherif E and Ando, Hidenori and Shimizu, Taro and Abdelkader, Hamdy and Ishima, Yu and Aly, Usama Farghaly and Sarhan, Hatem A and Ishida, Tatsuhiro

Journal:

Biological & pharmaceutical bulletin (2022): 129-135

Physical properties

Molecular weight	N/A
Solvent	Water

Antibody properties

Host

mouse

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on November 20, 2025