MUGlcU [4-Methylumbelliferyl-beta-D-glucuronide] CAS 881005-91-0

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Physical properties

Molecular weight	352.29
Solvent	DMSO

Spectral properties

Excitation (nm)	341
Emission (nm)	441

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Overview SDS Protocol

CAS

881005-91-0

Molecular weight

352.29

Excitation (nm)

341

Emission (nm)

441

MUGlcU is a fluorogenic MU substrate for detecting glucuronidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer. The organic and inorganic esters and glycosides of 7-hydroxy-4-methylcoumarin (4-methylumbelliferone, MU) are among the most commonly used fluorogenic substrates. These substrates yield water-soluble blue fluorescent coumarin fluorophores. MU develops maximum fluorescence above pH 10.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MUGlcU [4-Methylumbelliferyl-beta-D-glucuronide] *CAS 881005-91-0* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	283.857 µL	1.419 mL	2.839 mL	14.193 mL	28.386 mL
5 mM	56.771 µL	283.857 µL	567.714 µL	2.839 mL	5.677 mL
10 mM	28.386 µL	141.929 µL	283.857 µL	1.419 mL	2.839 mL

Molarity calculator

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Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Spectral properties

Excitation (nm)	341
Emission (nm)	441

Images

Figure 1. Chemical structure for MUGlcU [4-Methylumbelliferyl-beta-D-glucuronide] *CAS 881005-91-0*

References

View all 4 references: Citation Explorer

Coumarin Schiff-bases: as antioxidant and possibly anti-inflammatory agents
Authors: Gacche RN, Gond DS, Dhole NA, Dawane BS.
Journal: J Enzyme Inhib Med Chem (2006): 157

Examination of lectins, polysaccharopeptide, polysaccharide, alkaloid, coumarin and trypsin inhibitors for inhibitory activity against human immunodeficiency virus reverse transcriptase and glycohydrolases
Authors: Wang HX, Ng TB.
Journal: Planta Med (2001): 669

Induction of indoleamine 2,3-dioxygenase in alveolar interstitial cells of mouse lung by bacterial lipopolysaccharide
Authors: Urade Y, Yoshida R, Kitamura H, Hayaishi O.
Journal: J Biol Chem (1983): 6621

Determination of dicumarol metabolites in bile of rats
Authors: Conway WD, Lee FH, Neufeld L.
Journal: J Pharm Sci (1975): 1158