MUGlcU [4-Methylumbelliferyl-beta-D-glucuronide] *CAS 881005-91-0*

MUGlcU

4-Methylumbelliferyl-beta-D-glucuronide; CAS 881005-91-0

MUGlcU is a fluorogenic MU substrate for detecting glucuronidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer. The organic and inorganic esters and glycosides of 7-hydroxy-4-methylcoumarin (4-methylumbelliferone, MU) are among the most commonly used fluorogenic substrates. These substrates yield water-soluble blue fluorescent coumarin fluorophores. MU develops maximum fluorescence above pH 10.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
14016	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MUGlcU [4-Methylumbelliferyl-beta-D-glucuronide] *CAS 881005-91-0* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	283.857 µL	1.419 mL	2.839 mL	14.193 mL	28.386 mL
5 mM	56.771 µL	283.857 µL	567.714 µL	2.839 mL	5.677 mL
10 mM	28.386 µL	141.929 µL	283.857 µL	1.419 mL	2.839 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	352.29 g/mol	=	mL	x	mM	=	mmol

References

View all 4 references: Citation Explorer

Coumarin Schiff-bases: as antioxidant and possibly anti-inflammatory agents

Authors:

Gacche RN, Gond DS, Dhole NA, Dawane BS.

Journal:

J Enzyme Inhib Med Chem (2006): 157

Examination of lectins, polysaccharopeptide, polysaccharide, alkaloid, coumarin and trypsin inhibitors for inhibitory activity against human immunodeficiency virus reverse transcriptase and glycohydrolases

Authors:

Wang HX, Ng TB.

Journal:

Planta Med (2001): 669

Induction of indoleamine 2,3-dioxygenase in alveolar interstitial cells of mouse lung by bacterial lipopolysaccharide

Authors:

Urade Y, Yoshida R, Kitamura H, Hayaishi O.

Journal:

J Biol Chem (1983): 6621

Determination of dicumarol metabolites in bile of rats

Authors:

Conway WD, Lee FH, Neufeld L.

Journal:

J Pharm Sci (1975): 1158

Physical properties

Molecular weight	352.29
Solvent	DMSO

Spectral properties

Excitation (nm)	341
Emission (nm)	441

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200
CAS	881005-91-0

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Page updated on October 13, 2025