Name: OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor
Brand: AAT Bioquest
SKU: 21510
Price: 308 USD
Availability: InStock

OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor

OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor is a mitochondria-targeted red fluorescent probe that selectively detects lipid peroxidation in mitochondrial membranes, compatible with TRITC filters for multiplexed imaging.

Mitochondria-Specific Targeting: Selectively accumulates in mitochondria for precise localization of lipid peroxidation detection
Live Cell Compatible: Enables real-time monitoring of oxidative damage in living cells without fixation
Versatile Detection Methods: Red fluorescence signal (590 nm) compatible with microscopy, flow cytometry, and plate readers

Fluorescence response of OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor (1000 nM) in HeLa cells with or without Erastin (10 µM) treatment at 37 ºC in a 5% CO2 incubator for 30 minutes. The fluorescence intensities were monitored with fluorescence microscopy using Cy3 filter.

Protocol

SDS

Catalog	Size	Price	Quantity
21510	5x100 ug	Price

Overview

A wide range of diseases is considered to result from mitochondrial oxidative damage that is associated with the lipid peroxidation of mitochondrial inner membranes. There are no specific methods to assess mitochondrial lipid peroxidation in live cells. To address this unmet need, AAT Bioquest has developed the OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor, a fluorescent mitochondria-targeted probe that detects lipid peroxidation in live cells. OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor enters cells rapidly, and selectively accumulates in mitochondria. It has a high specificity for the detection of mitochondrial lipid peroxidation. Mitochondrial lipid peroxidation results in a great change in fluorescence at 590 nm, which can conveniently be monitored by fluorimetry, fluorescence microscopy or a fluorescence microplate reader.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of OxiVision™ Red Mitochondrial Lipid Peroxidation Sensor to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	118.596 µL	592.979 µL	1.186 mL	5.93 mL	11.86 mL
5 mM	23.719 µL	118.596 µL	237.192 µL	1.186 mL	2.372 mL
10 mM	11.86 µL	59.298 µL	118.596 µL	592.979 µL	1.186 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	843.2 g/mol	=	mL	x	mM	=	mmol

References

View all 50 references: Citation Explorer

Mitochondrial lipid peroxidation is necessary but not sufficient for induction of ferroptosis.

Authors:

Huan, He and Lyamzaev, Konstantin G and Panteleeva, Alisa A and Chernyak, Boris V

Journal:

Frontiers in cell and developmental biology (2024): 1452824

A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.

Authors:

Hai, Yongrui and Fan, Renming and Zhao, Ting and Lin, Ruizhuo and Zhuang, Junyan and Deng, Aohua and Meng, Shanshui and Hou, Zhuang and Wei, Gaofei

Journal:

Pharmacological research (2024): 107115

Mitochondrial miR-12294-5p-Regulated Copper Exposure-Caused Mitochondrial-Dependent Ferroptosis by Targeted Inhibition of CISD1 in Chicken Hepatocytes.

Authors:

Zhong, Gaolong and Wang, MengRan and Sun, Bingxia and Ma, Feiyang and Yu, Wenlan and Hu, Lianmei and Liao, Jianzhao and Tang, Zhaoxin

Journal:

Journal of agricultural and food chemistry (2024): 15948-15958

A platinum(IV)-artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy.

Authors:

Fan, Renming and Deng, Aohua and Lin, Ruizhuo and Zhang, Shuo and Cheng, Caiyan and Zhuang, Junyan and Hai, Yongrui and Zhao, Minggao and Yang, Le and Wei, Gaofei

Journal:

MedComm (2024): e570

Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes.

Authors:

Lyamzaev, Konstantin G and Huan, He and Panteleeva, Alisa A and Simonyan, Ruben A and Avetisyan, Armine V and Chernyak, Boris V

Journal:

Biomolecules (2024)

Physical properties

Molecular weight	843.20
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure

Instrument settings

Fluorescence microscope
Excitation	Cy3 Filter
Emission	Cy3 Filter
Recommended plate	Black wall/clear bottom

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on April 2, 2026