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Pluronic® F-127 *Cell culture tested *

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Physical properties
Molecular weight~13000
SolventWater
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRoom temperature (10-25 °C)
UNSPSC12352200

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CAS
9003-11-6
Molecular weight
~13000
Pluronic® F-127 is a nonionic surfactant that is 100% active and relatively non-toxic to cells, and frequently used with dye AM esters to improve their water solubility. It is soluble at low temperature, but gels at room temperature.

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Citations


View all 32 citations: Citation Explorer
Agonist-Induced Ca2+ Signaling in HEK-293-Derived Cells Expressing a Single IP3 Receptor Isoform
Authors: Kochkina, Ekaterina N and Kopylova, Elizaveta Е and Rogachevskaja, Olga A and Kovalenko, Nina P and Kabanova, Natalia V and Kotova, Polina D and Bystrova, Marina F and Kolesnikov, Stanislav S
Journal: Cells (2024): 562
Analysis of Fatty Acid Metabolism in Fetal and Failing Hearts by Single-Cell RNA Sequencing Revealed SLC27A6 as a Critical Gene in Heart Maturation
Authors: Zhu, Wenjia and Zheng, Yufan and Liu, Jiaying and Zhao, Chao and Sun, Ning and Qu, Xiuxia and Yang, Hui
Journal: Acta Cardiologica Sinica (2023): 580
Functional organization of visual responses in the octopus optic lobe
Authors: Pungor, Judit R and Allen, V Angelique and Songco-Casey, Jeremea O and Niell, Cristopher M
Journal: bioRxiv (2023): 2023--02
CVD-associated SNPs with regulatory potential drive pathologic non-coding RNA expression
Authors: Zhu, Chaonan and Baumgarten, Nina and Wu, Meiqian and Wang, Yue and Das, Arka Provo and Kaur, Jaskiran and Ardakani, Fatemeh Behjati and Duong, Thanh Thuy and Pham, Minh Duc and Duda, Maria and others,
Journal: bioRxiv (2023): 2023--02
Design, Synthesis, and Biological Evaluation of the First Radio-Metalated Neurotensin Analogue Targeting Neurotensin Receptor 2
Authors: Bodin, Sacha and Previti, Santo and Jestin, Emmanuelle and Vimont, Delphine and Ait-Arsa, Imade and Lamare, Frédéric and Rémond, Emmanuelle and Hindi{\'e}, Elif and Cavelier, Florine and Morgat, Clément
Journal: ACS Omega (2023)
CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes
Authors: Zhu, Chaonan and Baumgarten, Nina and Wu, Meiqian and Wang, Yue and Das, Arka Provo and Kaur, Jaskiran and Ardakani, Fatemeh Behjati and Duong, Thanh Thuy and Pham, Minh Duc and Duda, Maria and others,
Journal: Human Genomics (2023): 1--17
FTO-mediated m6A demethylation regulates GnRH expression in the hypothalamus via the PLC$\beta$3/Ca2+/CAMK signalling pathway
Authors: Zang, Shaolian and Yin, Xiaoqin and Li, Pin
Journal: Communications Biology (2023): 1297
Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia--Reperfusion Injury via the PERK-ATF4-CHOP Pathway
Authors: Wu, Yu and Fan, Xiaomei and Chen, Sha and Deng, Ling and Jiang, Lu and Yang, Shaonan and Dong, Zhi
Journal: International Journal of Molecular Sciences (2022): 544
Triple-Decker Sandwich Cultures of Intestinal Organoids for Long-Term Live Imaging, Uniform Perturbation, and Statistical Sampling
Authors: Cambra, Hailey M and Tallapragada, Naren P and Mannam, Prabhath and Breault, David T and Klein, Allon M
Journal: Current protocols (2022): e330
Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression
Authors: Wu, Yukang and Guo, Xudong and Han, Tong and Feng, Ke and Zhang, Peng and Xu, Yanxin and Yang, Yiwei and Xia, Yuchen and Chen, Yang and Xi, Jiajie and others,
Journal: Molecular Therapy-Nucleic Acids (2022): 481--497

References


View all 14 references: Citation Explorer
Pluronic F-127 as a Cell Carrier for Bone Tissue Engineering
Authors: Brunet-Maheu JM, Fern and es JC, de Lacerda CA, Shi Q, Benderdour M, Lavigne P.
Journal: J Biomater Appl. (2008)
Photochromic soft materials: flavylium compounds incorporated into pluronic F-127 hydrogel matrixes
Authors: Pina F, Hatton TA.
Journal: Langmuir (2008): 2356
Novel hydrogel microspheres of chitosan and pluronic F-127 for controlled release of 5-fluorouracil
Authors: Rokhade AP, Shelke NB, Patil SA, Aminabhavi TM.
Journal: J Microencapsul (2007): 274
Thermal gellation and photo-polymerization of di-acrylated Pluronic F 127
Authors: Lee SY, Tae G, Kim YH.
Journal: J Biomater Sci Polym Ed (2007): 1335
Tissue-engineered lung: an in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth
Authors: Cortiella J, Nichols JE, Kojima K, Bonassar LJ, Dargon P, Roy AK, Vacant MP, Niles JA, Vacanti CA.
Journal: Tissue Eng (2006): 1213
Pluronic F-127 affects the regulation of cytoplasmic Ca2+ in neuronal cells
Authors: Sutachan JJ, Montoya GJ, Xu F, Chen D, Blanck TJ, Recio-Pinto E.
Journal: Brain Res (2006): 131
In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of Azone and Transcutol
Authors: Escobar-Chavez JJ, Quintanar-Guerrero D, Ganem-Quintanar A.
Journal: Drug Dev Ind Pharm (2005): 447
Experimental study of modified bio-derived material by pluronic F-127 in vitro
Authors: Ren YX, Yang ZM, Li XQ.
Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2003): 52
Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels
Authors: Shawesh A, Kallioinen S, Antikainen O, Yliruusi J.
Journal: Pharmazie (2002): 690
Pluronic F-127 gels as a vehicle for topical formulations of indomethacin and rheological behaviour of these formulations
Authors: Shawesh A, Kallioinen S, Hellen L, Antikainen O, Yliruusi J.
Journal: Pharmazie (2002): 186