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Pluronic® F-127 *Cell culture tested *

Chemical structure for Pluronic® F-127 *Cell culture tested *.
Chemical structure for Pluronic® F-127 *Cell culture tested *.
Ordering information
Price ()
Catalog Number20050
Unit Size
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Additional ordering information
InternationalSee distributors
ShippingStandard overnight for United States, inquire for international
Physical properties
Molecular weight13000
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRoom temperature (10-25 °C)


Molecular weight
Pluronic® F-127 is a nonionic surfactant that is 100% active and relatively non-toxic to cells, and frequently used with dye AM esters to improve their water solubility. It is soluble at low temperature, but gels at room temperature.


Common stock solution preparation

Table 1. Volume of Water needed to reconstitute specific mass of Pluronic® F-127 *Cell culture tested * to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM7.692 µL38.462 µL76.923 µL384.615 µL769.231 µL
5 mM1.538 µL7.692 µL15.385 µL76.923 µL153.846 µL
10 mM769.231 nL3.846 µL7.692 µL38.462 µL76.923 µL

Molarity calculator

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Differing effects of estrogen deficiency on the contractile function of atrial and ventricular myocardium
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Human TRPV1 and TRPA1 are receptors for bacterial quorum sensing molecules
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View all 14 references: Citation Explorer
Pluronic F-127 as a Cell Carrier for Bone Tissue Engineering
Authors: Brunet-Maheu JM, Fern and es JC, de Lacerda CA, Shi Q, Benderdour M, Lavigne P.
Journal: J Biomater Appl. (2008)
Photochromic soft materials: flavylium compounds incorporated into pluronic F-127 hydrogel matrixes
Authors: Pina F, Hatton TA.
Journal: Langmuir (2008): 2356
Novel hydrogel microspheres of chitosan and pluronic F-127 for controlled release of 5-fluorouracil
Authors: Rokhade AP, Shelke NB, Patil SA, Aminabhavi TM.
Journal: J Microencapsul (2007): 274
Thermal gellation and photo-polymerization of di-acrylated Pluronic F 127
Authors: Lee SY, Tae G, Kim YH.
Journal: J Biomater Sci Polym Ed (2007): 1335
Tissue-engineered lung: an in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth
Authors: Cortiella J, Nichols JE, Kojima K, Bonassar LJ, Dargon P, Roy AK, Vacant MP, Niles JA, Vacanti CA.
Journal: Tissue Eng (2006): 1213
Pluronic F-127 affects the regulation of cytoplasmic Ca2+ in neuronal cells
Authors: Sutachan JJ, Montoya GJ, Xu F, Chen D, Blanck TJ, Recio-Pinto E.
Journal: Brain Res (2006): 131
In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of Azone and Transcutol
Authors: Escobar-Chavez JJ, Quintanar-Guerrero D, Ganem-Quintanar A.
Journal: Drug Dev Ind Pharm (2005): 447
Experimental study of modified bio-derived material by pluronic F-127 in vitro
Authors: Ren YX, Yang ZM, Li XQ.
Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2003): 52
Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels
Authors: Shawesh A, Kallioinen S, Antikainen O, Yliruusi J.
Journal: Pharmazie (2002): 690
Pluronic F-127 gels as a vehicle for topical formulations of indomethacin and rheological behaviour of these formulations
Authors: Shawesh A, Kallioinen S, Hellen L, Antikainen O, Yliruusi J.
Journal: Pharmazie (2002): 186