PRO-TAO-3 [equivalent to TO-PRO-3]

PRO-TAO-3

equivalent to TO-PRO-3

PRO-TAO-3 is the same molecule to TO-PRO®-3 stain. TO-PRO®-3 and the other monomeric cyanine stains have wide applicability due to their low background and bright fluorescence. It is a carbocyanine monomer nucleic acid stain that can be well excited by a red laser at 633 nm or 647 nm with far-red fluorescence similar to Cy®5 dyes. It is useful as a nuclear counterstain and dead cell indicator. It is selective for detecting dsDNA (double-stranded nucleic acids). The cell-impermeable PRO-TTO-3 is widely used for flow cytometry and fluorescence microscopy as a long-wavelength fluorescence well separated from green and red fluorophores in multicolor applications. TO-PRO® is the trademark of ThermoFisher Scientific.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
17565	1 mL	Price

References

View all 50 references: Citation Explorer

Anti-inflammatory functions of the glucocorticoid receptor require DNA binding.

Authors:

Escoter-Torres, Laura and Greulich, Franziska and Quagliarini, Fabiana and Wierer, Michael and Uhlenhaut, Nina Henriette

Journal:

Nucleic acids research (2020)

Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction.

Authors:

Clementi, Elena and Inglin, Larissa and Beebe, Erin and Gsell, Corina and Garajova, Zuzana and Markkanen, Enni

Journal:

BMC biology (2020): 36

DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain.

Authors:

Kyono, Yasuhiro and Raj, Samhitha and Sifuentes, Christopher J and Buisine, Nicolas and Sachs, Laurent and Denver, Robert J

Journal:

Developmental biology (2020): 180-196

Mithramycin selectively attenuates DNA-damage-induced neuronal cell death.

Authors:

Makarevich, Oleg and Sabirzhanov, Boris and Aubrecht, Taryn G and Glaser, Ethan P and Polster, Brian M and Henry, Rebecca J and Faden, Alan I and Stoica, Bogdan A

Journal:

Cell death & disease (2020): 587

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis.

Authors:

Shao, Zhengping and Flynn, Ryan A and Crowe, Jennifer L and Zhu, Yimeng and Liang, Jialiang and Jiang, Wenxia and Aryan, Fardin and Aoude, Patrick and Bertozzi, Carolyn R and Estes, Verna M and Lee, Brian J and Bhagat, Govind and Zha, Shan and Calo, Eliezer

Journal:

Nature (2020): 291-296

Physical properties

Molecular weight	671.42
Solvent	DMSO

Spectral properties

Extinction coefficient (cm ^-1 M ^-1)	102000
Excitation (nm)	642
Emission (nm)	657
Quantum yield	0.11 ¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501
CAS	157199-63-8

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Page updated on July 12, 2023