Name: Psoralen-PEG3-Biotin
Brand: AAT Bioquest
SKU: 39050
Availability: InStock

Psoralen-PEG3-Biotin

Psoralen-PEG3-Biotin is a photoactivatable reagent for biotinylating DNA or RNA. Psoralen-PEG3-Biotin has a psoralen group that can intercalate into double-stranded DNA or RNA and form covalent bonds with thymine and other pyrimidine bases when exposed to UV light (around 350 nm). Psoralen-PEG3-Biotin contains a polyethylene glycol (PEG) spacer arm that enhances the solubility and accessibility of the biotin moiety. Psoralen-PEG3-Biotin is used for selective labeling of cell surface proteins, biotinylation of hyaluronan, labeling of endotoxin for receptor binding studies, and crosslinking of nucleic acids for genomic investigations. It can also be used to study nucleic acid and protein interactions.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
39050	1 mg	Price
39051	5 mg	Price

References

View all 50 references: Citation Explorer

Mutations in AcrR and RNA Polymerase Confer High-Level Resistance to Psoralen-UVA Irradiation.

Authors:

Worley, Travis K and Weber, Emma A and Acott, Jedidiah D and Shimpi, Rahul S and Cole, Jessica M and Courcelle, Charmain T and Courcelle, Justin

Journal:

Journal of bacteriology (2023): e0012623

Force-Dependent Intercalative Bulky DNA Adduct Formation Detected by Single-Molecule Stretching.

Authors:

Liu, Yajun and Pei, Yufeng and Xu, Jingjing and Cheng, Yuanlei and Tong, Qingyi and You, Huijuan

Journal:

Analytical chemistry (2022): 13623-13630

ERCC1-XPF targeting to psoralen-DNA crosslinks depends on XPA and FANCD2.

Authors:

Sabatella, Mariangela and Pines, Alex and Slyskova, Jana and Vermeulen, Wim and Lans, Hannes

Journal:

Cellular and molecular life sciences : CMLS (2020): 2005-2016

2D Gel Electrophoresis to Detect DNA Replication and Recombination Intermediates in Budding Yeast.

Authors:

Zardoni, Luca and Nardini, Eleonora and Liberi, Giordano

Journal:

Methods in molecular biology (Clifton, N.J.) (2020): 43-59

The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks.

Authors:

Albelazi, Mustafa S and Martin, Peter R and Mohammed, Soran and Mutti, Luciano and Parsons, Jason L and Elder, Rhoderick H

Journal:

Genes (2019)

Physical properties

Molecular weight	688.79
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C)
UNSPSC	12171501

Documents

Protocol
Safety Data Sheet
Certificate of Analysis

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Page updated on October 24, 2025