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ReadiUse™ probenecid, sodium salt
Water-soluble
Probenecid is an inhibitor of organic-anion transporters located in cell membranes. These transporters often extrude fluorescent indicators from cells, and therefore contribute to poor dye retention. This phenomenon usually causes high background in the assays that require the good retention of the dye indicators inside cells. The use of probenecid to inhibit the transporter activity, and thus to reduce leakage of the intracellular dye indicators is a common method for reducing fluorescence background of calcium assays. The commonly used free acid form of probenecid requires the use of 1 M NaOH to dissolve it due to its poor water solubility in neutral water. AAT Bioquest offer the convenient Readiuse™ water-soluble and heat-stable probenecid in the format of a powder, solution or tablet. They are convenient to use and are as effective as the free acid form at the same concentration. Each vial is directly dissolved in 100 mL buffer to make 2.5 mM final concentration of probenecid for your assays.
Chemical structure for ReadiUse™ probenecid, sodium salt *Water-soluble*
Chemical structure for ReadiUse™ probenecid, sodium salt *Water-soluble*
CatalogSize
Price
Quantity
2006110x77 mg
Price
 
Physical properties

Molecular weight307.34
SolventWater
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageRoom temperature (10-25 °C); Minimize light exposure
UNSPSC12352200
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Page updated on October 8, 2025