RH 237 [N-(4-Sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, inner salt]

RH 237

N-(4-Sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, inner salt

RH 237, also called N-(4-sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, is a neuron-tracing dye. It is used for monitoring membrane potential, synaptic activity and ion channel activity of neurons.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
21480	5 mg	Price

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of RH 237 [N-(4-Sulfobutyl)-4-(6-(4-(dibutylamino)phenyl)hexatrienyl)pyridinium, inner salt] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	201.329 µL	1.007 mL	2.013 mL	10.066 mL	20.133 mL
5 mM	40.266 µL	201.329 µL	402.658 µL	2.013 mL	4.027 mL
10 mM	20.133 µL	100.664 µL	201.329 µL	1.007 mL	2.013 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
mg	÷	496.7 g/mol	=	mL	x	mM	=	mmol

Citations

View all 6 citations: Citation Explorer

The effect of sex and age on ex vivo cardiac electrophysiology: insight from a guinea pig model

Authors:

Haq, Kazi T and Cooper, Blake L and Berk, Fiona and Posnack, Nikki G

Journal:

American Journal of Physiology-Heart and Circulatory Physiology (2022)

Optocardiography and electrophysiology studies of ex vivo langendorff-perfused hearts

Authors:

Swift, Luther M and Jaimes III, Rafael and McCullough, Damon and Burke, Morgan and Reilly, Marissa and Maeda, Takuya and Zhang, Hanyu and Ishibashi, Nobuyuki and Rogers, Jack M and Posnack, Nikki Gillum

Journal:

Journal of visualized experiments: JoVE (2019)

Translational Physiology: Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds

Authors:

Hull, Christina M and Genge, Christine E and Hobbs, Yuki and Rayani, Kaveh and Lin, Eric and Gunawan, Marvin and Shafaattalab, Sanam and Tibbits, Glen F and Claydon, Tom W

Journal:

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (2019): R921

Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds

Authors:

Hull, Christina M and Genge, Christine E and Hobbs, Yuki and Rayani, Kaveh and Lin, Eric and Gunawan, Marvin and Shafaattalab, Sanam and Tibbits, Glen F and Claydon, Tom W

Journal:

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (2019): R921--R931

Age-associated changes in electrical function of the zebrafish heart

Authors:

Stoyek, Matthew R and Rog-Zielinska, Eva A and Quinn, T Alex and er, undefined

Journal:

Progress in biophysics and molecular biology (2018)

References

View all 11 references: Citation Explorer

Simultaneous optical imaging of membrane potential and intracellular calcium

Authors:

Fast VG., undefined

Journal:

J Electrocardiol (2005): 107

Contrasting effects of ischemia on the kinetics of membrane voltage and intracellular calcium transient underlie electrical alternans

Authors:

Lakireddy V, Baweja P, Syed A, Bub G, Boutjdir M, El-Sherif N.

Journal:

Am J Physiol Heart Circ Physiol (2005): H400

Second-harmonic generation sensitivity to transmembrane potential in normal and tumor cells

Authors:

Sacconi L, D'Amico M, Vanzi F, Biagiotti T, Antolini R, Olivotto M, Pavone FS.

Journal:

J Biomed Opt (2005): 24014

Intracellular Ca dynamics in ventricular fibrillation

Authors:

Omichi C, Lamp ST, Lin SF, Yang J, Baher A, Zhou S, Attin M, Lee MH, Karagueuzian HS, Kogan B, Qu Z, Garfinkel A, Chen PS, Weiss JN.

Journal:

Am J Physiol Heart Circ Physiol (2004): H1836

Effects of electrical shocks on Cai2+ and Vm in myocyte cultures

Authors:

Fast VG, Cheek ER, Pollard AE, Ideker RE.

Journal:

Circ Res (2004): 1589

Physical properties

Molecular weight	496.7
Solvent	DMSO

Spectral properties

Excitation (nm)	550
Emission (nm)	786

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on October 8, 2025