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SunRed™ SE
Although sulforhodamine 101 acid chloride (also called Texas Red®) is the most popular labeling reagent of sulfonyl chloride, it is quite unstable in water, especially at the higher pH required for reaction with aliphatic amines. Texas Red (TR) reacts with both aliphatic amines and aromatic amines indiscriminatingly. In addition, the labeling efficiency of Texas Red is extremely low compared to dye succinimidyl esters. SunRed™ SE is a succinimidyl ester. It is an excellent replacement for Texas Red. SunRed reacts with amine compounds such as amino acids, peptides and proteins to give bright red fluorescent conjugates that are extremely stable. Compared to Texas Red, SunRed has much higher labeling efficiency, and more importantly the resulted conjugate is more fluorescent and water soluble than the corresponding Texas Red conjugate. The conjugates of SunRed have the identical excitation and emission wavelengths to those of Texas Red. Our in-house studies indicated that SunRed is more stable than Texas Red under the same labeling conditions. It is extremely useful for labeling hydrophobic peptides, giving the fluorescent conjugates that are much easier to be purified and more water soluble to use.
Texas Red® and SunRed™ SE were respectively mixed with Gly-gly-Ser-Ser-Arg-Trp in 1:1 molar ratio at pH=9.0 under the same conditions.The resulted conjugates were purified by HPLC using a reverse phase C18 column.
Texas Red® and SunRed™ SE were respectively mixed with Gly-gly-Ser-Ser-Arg-Trp in 1:1 molar ratio at pH=9.0 under the same conditions.The resulted conjugates were purified by HPLC using a reverse phase C18 column.
CatalogSize
Price
Quantity
4725 mg
Price
4781 mg
Price
 
Physical properties

Molecular weight1123.34
SolventDMSO
Spectral properties

Correction factor (280 nm)0.366
Excitation (nm)592
Emission (nm)609
Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Page updated on October 5, 2025