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Tide Fluor™ 1 CPG [TF1 CPG] *500 Å* *Superior replacement for EDANS*

Related products
Tide Fluor™ 1 succinimidyl ester [TF1 SE]*Superior replacement for EDANS*
Tide Fluor™ 2 acid [TF2 acid] *Superior replacement for fluorescein*
Tide Fluor™ 2 amine [TF2 amine] *Superior replacement for fluorescein*
Tide Fluor™ 2 maleimide [TF2 maleimide] *Superior replacement for fluorescein*
Tide Fluor™ 2, succinimidyl ester [TF2 SE]*Superior replacement for fluorescein*
Tide Fluor™ 2 azide [TF2 azide]
Tide Fluor™ 2 alkyne [TF2 alkyne]
Tide Fluor™ 3 azide [TF3 azide]
Tide Fluor™ 3 alkyne [TF3 alkyne]
Tide Fluor™ 3 acid [TF3 acid] *Superior replacement for Cy3*
Tide Fluor™ 3 amine [TF3 amine] *Superior replacement for Cy3*
Tide Fluor™ 3 maleimide [TF3 maleimide] *Superior replacement for Cy3*
Tide Fluor™ 3 succinimidyl ester [TF3 SE]*Superior replacement for Cy3*
Tide Fluor™ 5WS azide [TF5WS azide]
Tide Fluor™ 5WS alkyne [TF5WS alkyne]
Tide Fluor™ 5WS acid [TF5WS acid] *Superior replacement for Cy5*
Tide Fluor™ 5WS amine [TF5WS amine] *Superior replacement for Cy5*
Tide Fluor™ 5WS maleimide [TF5WS maleimide] *Superior replacement for Cy5*
Tide Fluor™ 5WS succinimidyl ester [TF5WS SE]*Superior replacement for Cy5*
Tide Fluor™ 4 acid [TF4 acid] *Superior replacement for ROX and Texas Red*
Tide Fluor™ 4 amine [TF4 amine] *Superior replacement for ROX and Texas Red*
Tide Fluor™ 4 maleimide [TF4 maleimide] *Superior replacement for ROX and Texas Red*
Tide Fluor™ 4, succinimidyl ester [TF4 SE]*Superior replacement for ROX and Texas Red*
Tide Fluor™ 6WS acid [TF6WS acid] *Superior replacement for Cy5.5*
Tide Fluor™ 6WS amine [TF6WS amine] *Superior replacement for Cy5.5*
Tide Fluor™ 6WS maleimide [TF6WS maleimide] *Superior replacement for Cy5.5*
Tide Fluor™ 6WS succinimidyl ester [TF6WS SE]*Superior replacement for Cy5.5*
Tide Fluor™ 4 azide [TF4 azide]
Tide Fluor™ 4 alkyne [TF4 alkyne]
Tide Fluor™ 6WS azide [TF6WS azide]
Tide Fluor™ 6WS alkyne [TF6WS alkyne]
Tide Fluor™ 7WS azide [TF7WS azide]
Tide Fluor™ 7WS alkyne [TF7WS alkyne]
Tide Fluor™ 8WS azide [TF8WS azide] *Near Infrared Emission*
Tide Fluor™ 8WS alkyne [TF8WS alkyne] *Near Infrared Emission*
Tide Fluor™ 7WS acid [TF7WS acid] *Superior replacement for Cy7*
Tide Fluor™ 7WS amine [TF7WS amine] *Superior replacement for Cy7*
Tide Fluor™ 7WS maleimide [TF7WS maleimide] *Superior replacement for Cy7*
Tide Fluor™ 7WS, succinimidyl ester [TF7WS SE]*Superior replacement for Cy7*
Tide Fluor™ 8WS acid [TF8WS acid] *Near Infrared Emission*
Tide Fluor™ 8WS amine [TF8WS amine] *Near Infrared Emission*
Tide Fluor™ 8WS maleimide [TF8WS maleimide] *Near Infrared Emission*
Tide Fluor™ 8WS, succinimidyl ester [TF8WS SE]*Near Infrared Emission*
Tide Fluor™ 3WS maleimide [TF3WS maleimide] *Superior replacement for Cy3*
Tide Fluor™ 3WS acid [TF3WS acid] *Superior replacement for Cy3*
Tide Fluor™ 3WS succinimidyl ester [TF3WS SE] *Superior replacement for Cy3*
Tide Fluor™ 3WS amine [TF3WS amine] *Superior replacement for Cy3*
Tide Fluor™ 2WS acid [TF2WS acid] *Superior replacement for FITC*
Tide Fluor™ 2WS succinimidyl ester [TF2WS SE] *Superior replacement for FITC*
Tide Fluor™ 2WS maleimide [TF2WS Maleimide] *Superior replacement for FITC*
Tide Fluor™ 2WS Amine [TF2WS amine] *Superior replacement for FITC*
Tide Fluor™ 3 phosphoramidite [TF3 CEP] *Superior replacement to Cy3 phosphoramidite*
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TF1 is designed to be a superior fluorophore alternative to EDANS. TF1 has (a). much stronger absorption; (b). much stronger fluorescence intensity; and (3). much less environment-sensitive fluorescence. Additionally their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family a superior alternative to EDANS. TF1-labeled peptides and nucleotides exhibit much stronger fluorescence and higher sensitivity than the ones labeled with EDANS. In pairing with our Tide Quencher™ 1 (TQ1), a variety of FRET peptides and nucleotides can be developed for detecting proteases and molecular beacons with enhanced sensitivity and stability.
<p style="background: white; margin: 6.0pt 0in 6.0pt 0in;"><span style="font-size: 10.0pt;">Oligonucleotide synthesis is carried out by a stepwise addition of nucleotide residues to the 5'-terminus of the growing chain until the desired sequence is assembled. Each addition is referred to as a synthetic cycle and consists of four chemical reactions: d<span class="mw-headline">e-blocking (detritylation)</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, coupling</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, capping</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, and oxidation</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">.</span></span></p>
<p style="background: white; margin: 6.0pt 0in 6.0pt 0in;"><span style="font-size: 10.0pt;">Oligonucleotide synthesis is carried out by a stepwise addition of nucleotide residues to the 5'-terminus of the growing chain until the desired sequence is assembled. Each addition is referred to as a synthetic cycle and consists of four chemical reactions: d<span class="mw-headline">e-blocking (detritylation)</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, coupling</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, capping</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, and oxidation</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">.</span></span></p>
<p style="background: white; margin: 6.0pt 0in 6.0pt 0in;"><span style="font-size: 10.0pt;">Oligonucleotide synthesis is carried out by a stepwise addition of nucleotide residues to the 5'-terminus of the growing chain until the desired sequence is assembled. Each addition is referred to as a synthetic cycle and consists of four chemical reactions: d<span class="mw-headline">e-blocking (detritylation)</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, coupling</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, capping</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">, and oxidation</span><span style="user-select: none; display: inline-block; unicode-bidi: isolate;">.</span></span></p>
Ordering information
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Unit size
Catalog Number2240
Quantity
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Additional ordering information
Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
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Custom sizeInquire
ShippingStandard overnight for United States, inquire for international
Request quotation
Physical properties
SolventMeCN
Spectral properties
Correction Factor (280 nm)0.187
Extinction coefficient (cm -1 M -1)20000
Excitation (nm)341
Emission (nm)448
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
Spectrum
Citations
View all 7 citations: Citation Explorer
A mechanistic model to predict effects of cathepsin B and cystatin C on &beta;-amyloid aggregation and degradation
Authors: Perlenfein, Tyler J and Murphy, Regina M
Journal: Journal of Biological Chemistry (2017): jbc--M117
Real-Time Detection of a Self-Replicating RNA Enzyme
Authors: Olea, Charles and Joyce, Gerald F
Journal: Molecules (2016): 1310
Maternal serum glycosylated fibronectin as a point-of-care biomarker for assessment of preeclampsia
Authors: Rasanen, Juha and Quinn, Matthew J and Laurie, Amber and Bean, Eric and Roberts, Charles T and Nagalla, Srinivasa R and Gravett, Michael G
Journal: American journal of obstetrics and gynecology (2015): 82--e1
Development of Multi-Parametric/Multimodal Spectroscopy Apparatus for Characterization of Functional Interfaces
Authors: Zhou, Lang and Arugula, Mary and Easley, Christopher J and Shannon, Curtis and Simonian, Aleks and r, undefined
Journal: ECS Transactions (2015): 9--16
Array of biodegradable microrafts for isolation and implantation of living, adherent cells
Authors: Wang, Yuli and Phillips, Colleen N and Herrera, Gabriela S and Sims, Christopher E and Yeh, Jen Jen and Allbritton, Nancy L
Journal: RSC advances (2013): 9264--9272
References
View all 25 references: Citation Explorer
Evaluation of tetramethylrhodamine and black hole quencher 1 labeled probes and five commercial amplification mixes in TaqMan real-time RT-PCR assays for respiratory pathogens
Authors: Yang GP, Erdman DD, Tondella ML, Fields BS.
Journal: J Virol Methods (2009): 288
Time-resolved FRET method for typing polymorphic alleles of the human leukocyte antigen system by using a single DNA probe
Authors: Andreoni A, Bondani M, Nardo L.
Journal: Photochem Photobiol Sci (2009): 1202
Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer
Authors: Ogawa M, Kosaka N, Choyke PL, Kobayashi H.
Journal: Bioconjug Chem (2009): 147
The detection of platelet derived growth factor using decoupling of quencher-oligonucleotide from aptamer/quantum dot bioconjugates
Authors: Kim GI, Kim KW, Oh MK, Sung YM.
Journal: Nanotechnology (2009): 175503
Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening
Authors: Yu X, Sainz B, Jr., Uprichard SL.
Journal: Antimicrob Agents Chemother (2009): 4311