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Tide Fluor™ 3 phosphoramidite
TF3 CEP; Superior replacement to Cy3 phosphoramidite
Tide Fluor™ 3 (TF3) phosphoramidite is a high-performance alternative to Cy3 phosphoramidite for the in-synthesis labeling of oligonucleotides. TF3-labeled oligonucleotides share nearly identical fluorescence spectra to those labeled with Cy3, but the significantly larger quantum yield of TF3 produces a much brighter fluorescence signal with greater photostability than Cy3. When paired with our Tide Quencher™ 3 (TQ3), TF3 can be used to produce a variety of highly-sensitive FRET peptides and nucleotides for detecting protease activity as well as molecular beacons with enhanced sensitivity and stability.
Chemical structure for Tide Fluor™ 3 phosphoramidite [TF3 CEP] *Superior replacement to Cy3  phosphoramidite*.
Chemical structure for Tide Fluor™ 3 phosphoramidite [TF3 CEP] *Superior replacement to Cy3  phosphoramidite*.
CatalogSize
Price
Quantity
2274100 umoles
Price
 
Physical properties

Molecular weight1045.36
SolventMeCN
Spectral properties

Absorbance (nm)560
Extinction coefficient (cm -1 M -1)
75000
1
Excitation (nm)560
Emission (nm)580
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Page updated on October 13, 2025