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Tide Quencher™ 1 maleimide
TQ1 maleimide
TQ1 is designed to be a superior quencher alternative to DABCYL. Compared to DABCYL, TQ1 have (a). much stronger absorption; (b). much higher quenching efficiency; and (c). versatile reactive forms with desired solubility for labeling oligonucleotides and peptides. This TQ1 product is used for post-labeling thiol-modified oligonucleotides and cysteine-containing peptides.
<p>Dye maleimides are the most popular tool for conjugating dyes to a peptide, protein, antibody, thiol-modified oligonucleotide or nucleic acid through their SH group. Maleimides react readily with the thiol group of proteins, thiol-modified oligonucleotides, and other thiol-containing molecules under neutral conditions. The resulting dye conjugates are quite stable.</p>
<p>Dye maleimides are the most popular tool for conjugating dyes to a peptide, protein, antibody, thiol-modified oligonucleotide or nucleic acid through their SH group. Maleimides react readily with the thiol group of proteins, thiol-modified oligonucleotides, and other thiol-containing molecules under neutral conditions. The resulting dye conjugates are quite stable.</p>
CatalogSize
Price
Quantity
21965 mg
Price
 
Physical properties

Molecular weight412.46
SolventDMSO
Spectral properties

Absorbance (nm)492
Correction factor (260 nm)0.147
Correction factor (280 nm)0.194
Extinction coefficient (cm -1 M -1)
20000
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
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Page updated on October 12, 2025