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Tide Quencher™ 3 alkyne
TQ3 alkyne
TQ3 is designed to be a superior quencher to TAMRA, TF3 and Cy3. TQ3 has (a). much stronger absorption; (b). much higher quenching efficiency; and (c). versatile reactive forms with desired solubility for labeling oligonucleotides and peptides. This TQ3 product is reactive to azides, and useful for click chemistry.
<p>Click chemistry is a method for attaching a&nbsp;probe&nbsp;or&nbsp;substrate&nbsp;of interest to a specific biomolecule, a process called&nbsp;bioconjugation. The possibility of attaching dyes&nbsp;and other&nbsp;reporter molecules&nbsp;has made click chemistry a very powerful tool for identifying, locating, and characterizing both old and new biomolecules. The classic click reaction is the copper-catalyzed reaction of an&nbsp;azide&nbsp;with an&nbsp;alkyne&nbsp;to form a 5-membered&nbsp;heteroatom&nbsp;ring, this reaction is commonly called Cu(I)-Catalyzed Azide-Alkyne&nbsp;Cycloaddition&nbsp;(CuAAC).</p>
<p>Click chemistry is a method for attaching a&nbsp;probe&nbsp;or&nbsp;substrate&nbsp;of interest to a specific biomolecule, a process called&nbsp;bioconjugation. The possibility of attaching dyes&nbsp;and other&nbsp;reporter molecules&nbsp;has made click chemistry a very powerful tool for identifying, locating, and characterizing both old and new biomolecules. The classic click reaction is the copper-catalyzed reaction of an&nbsp;azide&nbsp;with an&nbsp;alkyne&nbsp;to form a 5-membered&nbsp;heteroatom&nbsp;ring, this reaction is commonly called Cu(I)-Catalyzed Azide-Alkyne&nbsp;Cycloaddition&nbsp;(CuAAC).</p>
protocol
Protocol
sds
SDS
COA
CatalogSize
Price
Quantity
22325 mg
Price
 
Physical properties
Molecular weight490.58
SolventDMSO
Spectral properties
Absorbance (nm)573
Correction factor (260 nm)0.085
Correction factor (280 nm)0.091
Extinction coefficient (cm -1 M -1)
22000
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
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Page updated on October 12, 2025