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Tide Quencher™ 5WS succinimidyl ester
TQ5WS SE
TQ5WS is designed to be a superior quencher to Cy5, TF5 and Cy5.5. TQ5WS has (a). much stronger absorption; (b). much higher quenching efficiency; and (c). versatile reactive forms with desired solubility for labeling oligonucleotides and peptides. This TQ5WS product is primarily used for post-labeling of amino-modified oligonucleotides and the N-terminal or lysine residues of peptides.
<p>Dye NHS esters (or succinimidyl esters) are the most popular tool for conjugating dyes to a peptide, protein, antibody, amino-modified oligonucleotide or nucleic acid. NHS esters react readily with the primary amines (R-NH<sub>2</sub>) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The resulting dye conjugates are quite stable.</p>
<p>Dye NHS esters (or succinimidyl esters) are the most popular tool for conjugating dyes to a peptide, protein, antibody, amino-modified oligonucleotide or nucleic acid. NHS esters react readily with the primary amines (R-NH<sub>2</sub>) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The resulting dye conjugates are quite stable.</p>
protocol
Protocol
sds
SDS
COA
CatalogSize
Price
Quantity
20811 mg
Price
 
Physical properties
Molecular weight974.24
SolventDMSO
Spectral properties
Absorbance (nm)661
Correction factor (260 nm)0.072
Correction factor (280 nm)0.082
Extinction coefficient (cm -1 M -1)
130000
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure
UNSPSC12352200
Documents
Protocol
Safety Data Sheet
Certificate of Analysis
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Page updated on October 24, 2025